@prefix p66: <http://data.loterre.fr/ark:/67375/P66> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix uneskos: <http://purl.org/umu/uneskos#> .
@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix isothes: <http://purl.org/iso25964/skos-thes#> .

p66:-QXWD8ZSB-9
  skos:prefLabel "brain"@en, "encéphale"@fr ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-W928H8CG-5
  skos:prefLabel "c-fos"@fr, "c-fos"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-JX4578X6-C
  skos:prefLabel "plasticité synaptique"@fr, "synaptic plasticity"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-JHMV0S1K-G
  skos:prefLabel "facteur CREB"@fr, "CREB factor"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-F3R6HDD2-Z
  skos:prefLabel "protein kinase Mζ"@en, "protéine kinase Mζ"@fr ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-X1M4BRNP-Z
  skos:prefLabel "consolidation"@fr, "consolidation"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-RZ2X1NZ0-K
  skos:prefLabel "processus neurophysiologique"@fr, "neurophysiological process"@en ;
  a skos:Concept ;
  skos:narrower p66:-NG7QTM2N-0 .

p66: a skos:ConceptScheme .
p66:-NG7QTM2N-0
  dc:creator "Frank Arnould" ;
  dc:bibliographicCitation """<span class ="replaced2">	•	 Lømo, T. (2018). Discovering long‐term potentiation (LTP) – recollections and reflections on what came after. Acta Physiologica, 222(2), 1–1.  <a href="https://doi.org/10.1111/apha.12921">https://doi.org/10.1111/apha.12921</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Document type</span>: <span class="versal">historical study</span></p>, <span class="versal">literature review</span></p> <p><span class="tooltip-prop">• Access</span>: <span class="versal">closed</span></p>"""@en, """<span class ="replaced2">	•	 Lømo, T. (2018). Discovering long‐term potentiation (LTP) – recollections and reflections on what came after. Acta Physiologica, 222(2), 1–1.  <a href="https://doi.org/10.1111/apha.12921">https://doi.org/10.1111/apha.12921</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Type de document</span> : <span class="versal">étude historique</span></p>, <span class="versal">revue de la littérature</span></p> <p><span class="tooltip-prop">• Accès</span> : <span class="versal">fermé</span></p>"""@fr, """<span class ="replaced2">	•	 Lømo, T. (1966). Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation. Acta Physiologica Scandinavica, 68 (Suppl 277), 128.</span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Type de document</span> : <span class="versal">étude empirique</span></p> <p><span class="tooltip-prop">• Accès</span> : <span class="versal">fermé</span></p>"""@fr, """<span class ="replaced2">	•	 Bliss, T. V., & Lømo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. The Journal of Physiology, 232(2), 331–356.  <a href="https://doi.org/10.1113/jphysiol.1973.sp010274">https://doi.org/10.1113/jphysiol.1973.sp010274</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Document type</span>: <span class="versal">empirical study</span></p> <p><span class="tooltip-prop">• Access</span>: <span class="versal">closed</span></p>"""@en, """<span class ="replaced2">	•	 Nicoll, R. A. (2017). A brief history of long-term potentiation. Neuron, 93(2), 281–290.  <a href="https://doi.org/10.1016/j.neuron.2016.12.015">https://doi.org/10.1016/j.neuron.2016.12.015</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Document type</span>: <span class="versal">historical study</span></p> <p><span class="tooltip-prop">• Access</span>: <span class="versal">open</span></p>"""@en, """<span class ="replaced2">	•	 Bliss, T. V., & Lømo, T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. The Journal of Physiology, 232(2), 331–356.  <a href="https://doi.org/10.1113/jphysiol.1973.sp010274">https://doi.org/10.1113/jphysiol.1973.sp010274</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Type de document</span> : <span class="versal">étude empirique</span></p> <p><span class="tooltip-prop">• Accès</span> : <span class="versal">fermé</span></p>"""@fr, """<span class ="replaced2">	•	 Nicoll, R. A. (2017). A brief history of long-term potentiation. Neuron, 93(2), 281–290.  <a href="https://doi.org/10.1016/j.neuron.2016.12.015">https://doi.org/10.1016/j.neuron.2016.12.015</a></span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Type de document</span> : <span class="versal">étude historique</span></p> <p><span class="tooltip-prop">• Accès</span> : <span class="versal">ouvert</span></p>"""@fr, """<span class ="replaced2">	•	 Lømo, T. (1966). Frequency potentiation of excitatory synaptic activity in the dentate area of the hippocampal formation. Acta Physiologica Scandinavica, 68 (Suppl 277), 128.</span> <span class="reified-property-value xl-pref-label tooltip-html"><p><img src="resource/pics/infoBlue.png"/>	</p><div class="reified-tooltip tooltip-html-content"><p><span class="tooltip-prop">• Document type</span>: <span class="versal">empirical study</span></p> <p><span class="tooltip-prop">• Access</span>: <span class="versal">closed</span></p>"""@en ;
  skos:altLabel "long-term synaptic potentiation"@en, "LTP"@en, "potentialisation synaptique à long terme"@fr ;
  skos:related p66:-JHMV0S1K-G, p66:-QXWD8ZSB-9, p66:-X1M4BRNP-Z, p66:-W928H8CG-5, p66:-JX4578X6-C, p66:-G4T4V894-V, p66:-T0CV2HJ4-J, p66:-P3PC7CZ3-D, p66:-F3R6HDD2-Z ;
  skos:broader p66:-RZ2X1NZ0-K ;
  uneskos:memberOf p66:-Animal, p66:-Homme ;
  skos:exactMatch <https://en.wikipedia.org/wiki/Long-term_potentiation>, <https://fr.wikipedia.org/wiki/Potentialisation_à_long_terme>, <https://www.wikidata.org/wiki/Q1805481>, jvr:-W2XGSG36-S ;
  dc:modified "2023-03-15"^^xsd:date ;
  skos:prefLabel "potentialisation à long terme"@fr, "long-term potentiation"@en ;
  dc:created "2017-12-04"^^xsd:date ;
  skos:definition "Processus entraînant une augmentation durable (quelques heures à plusieurs semaines) de l'efficacité des synapses après une série de stimulations électriques à haute fréquence."@fr, "Process resulting in long-lasting increase in synapse efficiency (a few hours to several weeks) after a series of high-frequency electrical stimulation."@en ;
  a skos:Concept ;
  skos:inScheme p66: .

p66:-T0CV2HJ4-J
  skos:prefLabel "glutamate"@fr, "glutamate"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-P3PC7CZ3-D
  skos:prefLabel "mémoire"@fr, "memory"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-Animal
  skos:prefLabel "Animal non humain"@fr, "Nonhuman animal"@en ;
  a isothes:ConceptGroup ;
  skos:member p66:-NG7QTM2N-0 .

p66:-G4T4V894-V
  skos:prefLabel "cellule d'engramme"@fr, "engram cell"@en ;
  a skos:Concept ;
  skos:related p66:-NG7QTM2N-0 .

p66:-Homme
  skos:prefLabel "Human"@en, "Homme"@fr ;
  a isothes:ConceptGroup ;
  skos:member p66:-NG7QTM2N-0 .