@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-K8TQBZST-8 skos:prefLabel "DNA-Cytosine Methylases"@fr, "DNA-Cytosine Methylases"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-ZT2QPDZC-C . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-MGRMRXHX-S skos:prefLabel "Site-specific DNA-methyltransferase (adenine-specific)"@fr, "Site-Specific DNA-Methyltransferase (Adenine-Specific)"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-ZT2QPDZC-C . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KB4FD09B-4 skos:prefLabel "Methyltransferases"@fr, "Methyltransferases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZT2QPDZC-C . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-ZT2QPDZC-C mesh:allowableQualifier jvr:-CB30NGKB-3, jvr:-M63HSDM7-1, jvr:-G7KXQWSR-5, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-NHL3D2X0-S, jvr:-T2TS0S41-N, jvr:-CJXMKG5Q-F, jvr:-WK5F724J-1, jvr:-R3QWLHRG-V, jvr:-T9HQD7ST-J, jvr:-Q3979798-W, jvr:-S0CS1X5R-5, jvr:-N2WP45CN-V, jvr:-D0F21513-5, jvr:-XV06LPML-W, jvr:-NB0XHT3S-N, jvr:-BT300B3G-Q, jvr:-W6SQV79N-S, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-NFTHND7Q-8, jvr:-G30ZJ446-J, jvr:-WZF2ZR3L-B, jvr:-HQRFT0C6-B, jvr:-L6C0XPHT-4, jvr:-FWD2BGQ0-9, jvr:-THHNVC7V-3, jvr:-NKM836P1-M ; skos:hiddenLabel "EC 2.1.1.-"@en, "EC 2.1.1.-"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-MGRMRXHX-S, jvr:-K8TQBZST-8 ; skos:broader jvr:-KB4FD09B-4, jvr:-C15MGKVK-S ; owl:sameAs ; dc:modified "2003-07-09"^^xsd:date ; skos:altLabel "Modification Methylases"@en, "Méthyltransférases de modification de l'ADN"@fr, "DNA Modification Methyltransferases"@en, "Enzymes de modification de l'ADN"@fr ; skos:prefLabel "DNA modification methylases"@fr, "DNA Modification Methylases"@en ; mesh:registryNumber "EC 2.1.1.-" ; skos:definition "Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms."@en ; skos:inScheme jvr: ; dc:established "1989-01-01"^^xsd:date ; dc:created "1988-05-17"^^xsd:date . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-C15MGKVK-S skos:prefLabel "Enzymes de restriction-modification de l'ADN"@fr, "DNA Restriction-Modification Enzymes"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZT2QPDZC-C . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .