@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-ZKNX60PT-D skos:definition "The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system."@en ; skos:related jvr:-PT6PQGX2-9 ; mesh:allowableQualifier jvr:-D0F21513-5, jvr:-M63HSDM7-1, jvr:-CB30NGKB-3, jvr:-Z9TSGBXH-4, jvr:-BT300B3G-Q, jvr:-WZF2ZR3L-B, jvr:-L6C0XPHT-4, jvr:-G4R176S9-J, jvr:-FWD2BGQ0-9, jvr:-THHNVC7V-3, jvr:-G7KXQWSR-5, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-NFTHND7Q-8, jvr:-NB0XHT3S-N, jvr:-NHL3D2X0-S, jvr:-S0CS1X5R-5, jvr:-H7K65Q8S-Z, jvr:-XV06LPML-W, jvr:-CJXMKG5Q-F, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-TJHVZCRZ-0, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-G30ZJ446-J, jvr:-Q3979798-W, jvr:-R0ZCQ8X6-J, jvr:-NKM836P1-M ; mesh:pharmacologicalAction jvr:-CW1BZZWB-6, jvr:-M4W33FZ9-8 ; owl:sameAs ; skos:hiddenLabel "Levopa"@en, "Larodopa"@en, "Dopar"@en, "Dopaflex"@en ; dc:created "1999-01-01"^^xsd:date ; dc:modified "2018-06-30"^^xsd:date ; skos:altLabel "3-Hydroxy-L-tyrosine"@en, "3-Hydroxy-L-tyrosine"@fr, "L-Dopa"@en, "L-Dopa"@fr, "L-3,4-Dihydroxyphenylalanine"@en, "46627O600J"@fr, "46627O600J"@en ; skos:inScheme jvr: ; skos:broader jvr:-NQ6H8MJ6-6 ; a skos:Concept, mesh:Descriptor ; dc:established "1975-01-01"^^xsd:date ; skos:prefLabel "Lévodopa"@fr, "Levodopa"@en . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CW1BZZWB-6 skos:prefLabel "Agents dopaminergiques"@fr, "Dopamine Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M4W33FZ9-8 skos:prefLabel "Antiparkinson Agents"@en, "Antiparkinsoniens"@fr ; a mesh:Descriptor, skos:Concept . jvr:-PT6PQGX2-9 skos:prefLabel "Dopamine"@en, "Dopamine"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-ZKNX60PT-D . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NQ6H8MJ6-6 skos:prefLabel "Dopa"@fr, "Dihydroxyphenylalanine"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZKNX60PT-D .