@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-QL35BZGZ-C
  skos:prefLabel "Adaptor Proteins, Signal Transducing"@en, "Protéines adaptatrices de la transduction du signal"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-ZK611792-1 .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z5DFSCH8-2
  skos:prefLabel "Facteur de transcription STAT-6"@fr, "STAT6 Transcription Factor"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-LBBFVG4D-8
  skos:prefLabel "STAT3 Transcription Factor"@en, "Facteur de transcription STAT-3"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZK611792-1
  skos:altLabel "Facteurs transducteurs du signal et activateurs de la transcription"@fr, "STAT (Signal Transducers and Activators of Transcription) Proteins"@en, "Transducteurs du signal et activateurs de la transcription"@fr, "Facteurs transcriptionnels STAT"@fr, "Protéines STAT"@fr ;
  mesh:allowableQualifier jvr:-TJHVZCRZ-0, jvr:-HQRFT0C6-B, jvr:-FWD2BGQ0-9, jvr:-R0ZCQ8X6-J, jvr:-CJXMKG5Q-F, jvr:-Z9TSGBXH-4, jvr:-NB0XHT3S-N, jvr:-NHL3D2X0-S, jvr:-T2TS0S41-N, jvr:-Q3979798-W, jvr:-THHNVC7V-3, jvr:-G30ZJ446-J, jvr:-NKM836P1-M, jvr:-W6SQV79N-S, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-N2WP45CN-V, jvr:-WZF2ZR3L-B, jvr:-L6C0XPHT-4, jvr:-G7KXQWSR-5, jvr:-SBNWSM1T-R, jvr:-D0F21513-5, jvr:-XV06LPML-W, jvr:-BT300B3G-Q, jvr:-H7K65Q8S-Z, jvr:-WK5F724J-1, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8, jvr:-CB30NGKB-3, jvr:-M63HSDM7-1 ;
  skos:definition "A family of transcription factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated SIGNAL TRANSDUCTION. STAT transcription factors are recruited to the cytoplasmic region of CELL SURFACE RECEPTORS and are activated via PHOSPHORYLATION. Once activated they dimerize and translocate into the CELL NUCLEUS where they influence GENE expression. They play a role in regulating CELL GROWTH PROCESSES and CELL DIFFERENTIATION. STAT transcription factors are inhibited by SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS and PROTEIN INHIBITORS OF ACTIVATED STAT."@en ;
  dc:created "2005-06-30"^^xsd:date ;
  dc:modified "2016-02-18"^^xsd:date ;
  skos:broader jvr:-QL35BZGZ-C, jvr:-ZR7N1DVF-Z ;
  skos:prefLabel "Facteurs de transcription STAT"@fr, "STAT Transcription Factors"@en ;
  skos:narrower jvr:-LXXXNGH4-P, jvr:-Z5DFSCH8-2, jvr:-ZF7KCV6K-R, jvr:-LBBFVG4D-8, jvr:-K36BZM19-Z, jvr:-RW1WHD9M-B ;
  a skos:Concept, mesh:Descriptor ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D050791> ;
  dc:established "2006-01-01"^^xsd:date ;
  skos:inScheme jvr: .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-K36BZM19-Z
  skos:prefLabel "STAT5 Transcription Factor"@en, "Facteur de transcription STAT-5"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZR7N1DVF-Z
  skos:prefLabel "Facteurs de transcription"@fr, "Transcription Factors"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-ZK611792-1 .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-LXXXNGH4-P
  skos:prefLabel "Facteur de transcription STAT-2"@fr, "STAT2 Transcription Factor"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-ZF7KCV6K-R
  skos:prefLabel "STAT1 Transcription Factor"@en, "Facteur de transcription STAT-1"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RW1WHD9M-B
  skos:prefLabel "STAT4 Transcription Factor"@en, "Facteur de transcription STAT-4"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZK611792-1 .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .