@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H8MVH21N-V
  skos:prefLabel "Cytochrome P-450 CYP2B6"@fr, "Cytochrome P-450 CYP2B6"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MGPCJSVN-0
  skos:prefLabel "Benzopyrene Hydroxylase"@en, "Benzopyrene hydroxylase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-F92HWDSM-S
  skos:prefLabel "Cytochrome P-450 CYP2C8"@fr, "Cytochrome P-450 CYP2C8"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FH4FCBHX-C
  skos:prefLabel "7-Alkoxycoumarin O-Dealkylase"@en, "7-Alkoxycoumarin O-dealkylase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QW6NM13W-2
  skos:prefLabel "Cytochrome P-450 enzyme system"@fr, "Cytochrome P-450 Enzyme System"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-ZJXXGZ1B-L .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZJXXGZ1B-L
  mesh:allowableQualifier jvr:-G30ZJ446-J, jvr:-M63HSDM7-1, jvr:-SBNWSM1T-R, jvr:-NKM836P1-M, jvr:-FWD2BGQ0-9, jvr:-H7K65Q8S-Z, jvr:-W6SQV79N-S, jvr:-L6C0XPHT-4, jvr:-G7KXQWSR-5, jvr:-N2WP45CN-V, jvr:-S0CS1X5R-5, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-NFTHND7Q-8, jvr:-CB30NGKB-3, jvr:-HQRFT0C6-B, jvr:-T2TS0S41-N, jvr:-THHNVC7V-3, jvr:-XV06LPML-W, jvr:-CJXMKG5Q-F, jvr:-Q3979798-W, jvr:-TJHVZCRZ-0, jvr:-R3QWLHRG-V, jvr:-NHL3D2X0-S, jvr:-WK5F724J-1, jvr:-BT300B3G-Q, jvr:-T9HQD7ST-J, jvr:-WZF2ZR3L-B, jvr:-Z9TSGBXH-4 ;
  skos:altLabel "Microsomal P450"@fr, "Aryl-4-monooxygenase"@fr, "Aryl hydrocarbone hydroxylases"@fr, "Microsomal Monooxygenases"@en, "Monooxygénase non spécifique"@fr, "Microsomal monooxygenase"@fr ;
  dc:created "1974-11-11"^^xsd:date ;
  mesh:registryNumber "EC 1.14.14.1" ;
  skos:narrower jvr:-S817MB3N-K, jvr:-WBXGW4N6-S, jvr:-JPNSL7G2-B, jvr:-H8MVH21N-V, jvr:-WHF9N874-1, jvr:-CFTJ5FB2-5, jvr:-FH4FCBHX-C, jvr:-MGPCJSVN-0, jvr:-RW8Z30JT-4, jvr:-F92HWDSM-S ;
  skos:prefLabel "Aryl hydrocarbon hydroxylases"@fr, "Aryl Hydrocarbon Hydroxylases"@en ;
  a mesh:Descriptor, skos:Concept ;
  dc:established "1975-09-01"^^xsd:date ;
  skos:hiddenLabel "Xénobiotique monooxygénases"@fr, "EC 1.14.14.1"@fr, "EC 1.14.14.1"@en, "Xenobiotic monooxygenases"@fr, "Xenobiotic Monooxygenases"@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D001189> ;
  skos:definition "A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides. Monooxygenases that oxidize exogenous substrates."@en ;
  skos:inScheme jvr: ;
  skos:broader jvr:-QW6NM13W-2 ;
  dc:modified "2016-05-27"^^xsd:date .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-JPNSL7G2-B
  skos:prefLabel "Cytochrome P-450 CYP1A1"@en, "Cytochrome P-450 CYP1A1"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WBXGW4N6-S
  skos:prefLabel "Aniline hydroxylase"@fr, "Aniline Hydroxylase"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WHF9N874-1
  skos:prefLabel "Cytochrome P-450 CYP2D6"@fr, "Cytochrome P-450 CYP2D6"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-RW8Z30JT-4
  skos:prefLabel "Cytochrome P-450 CYP1A2"@fr, "Cytochrome P-450 CYP1A2"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CFTJ5FB2-5
  skos:prefLabel "Cytochrome P-450 CYP1B1"@fr, "Cytochrome P-450 CYP1B1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-S817MB3N-K
  skos:prefLabel "Cytochrome P-450 CYP2B1"@fr, "Cytochrome P-450 CYP2B1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-ZJXXGZ1B-L .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .