@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PJSP1GMX-T skos:prefLabel "Parasympathomimétiques"@fr, "Parasympathomimetics"@en ; a mesh:Descriptor, skos:Concept . jvr:-SX2QH895-B skos:prefLabel "Methacholine Compounds"@en, "Composés de méthacholine"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZDQ0GJKD-N . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZDQ0GJKD-N skos:altLabel "62-51-1 (Methacholine Chloride)"@fr, "62-51-1 (Methacholine Chloride)"@en, "03V657ZD3V"@fr, "03V657ZD3V"@en, "Acetyl-beta-methacholine Chloride"@en, "2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride"@en, "Mecholine"@en, "1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride"@fr, "1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride"@en, "Acetyl-2-methylcholine Chloride"@en, "0W5ETF9M2K"@fr, "0W5ETF9M2K"@en, "55-92-5 (parent)"@fr, "55-92-5 (parent)"@en ; mesh:allowableQualifier jvr:-S0CS1X5R-5, jvr:-R0ZCQ8X6-J, jvr:-R3QWLHRG-V, jvr:-H7K65Q8S-Z, jvr:-NHL3D2X0-S, jvr:-XV06LPML-W, jvr:-NB0XHT3S-N, jvr:-G4R176S9-J, jvr:-T9HQD7ST-J, jvr:-TJHVZCRZ-0, jvr:-THHNVC7V-3, jvr:-D0F21513-5, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-NFTHND7Q-8, jvr:-NKM836P1-M, jvr:-G30ZJ446-J, jvr:-CB30NGKB-3, jvr:-Q3979798-W, jvr:-L6C0XPHT-4, jvr:-WK5F724J-1, jvr:-BT300B3G-Q, jvr:-SBNWSM1T-R, jvr:-M63HSDM7-1, jvr:-FWD2BGQ0-9 ; owl:sameAs ; mesh:pharmacologicalAction jvr:-TGW16G8Q-4, jvr:-X079LVDZ-K, jvr:-B03RFCHF-1, jvr:-PJSP1GMX-T ; skos:broader jvr:-SX2QH895-B ; a mesh:Descriptor, skos:Concept ; dc:established "1991-01-01"^^xsd:date ; skos:inScheme jvr: ; dc:modified "2016-07-01"^^xsd:date ; skos:hiddenLabel "Acetyl-beta-methylcholine"@fr, "Acetyl-beta-methylcholine"@en, "Mecholyl"@en, "Provokit"@en, "Methacholine"@en, "Méthacholine"@fr, "Provocholine"@en ; skos:definition "A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116)"@en ; dc:created "1990-04-24"^^xsd:date ; skos:prefLabel "Chlorure de méthacholine"@fr, "Methacholine Chloride"@en . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TGW16G8Q-4 skos:prefLabel "Agonistes muscariniques"@fr, "Muscarinic Agonists"@en ; a mesh:Descriptor, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-X079LVDZ-K skos:prefLabel "Miotics"@en, "Myotiques"@fr ; a mesh:Descriptor, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-B03RFCHF-1 skos:prefLabel "Bronchoconstricteurs"@fr, "Bronchoconstrictor Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .