@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZB2RQRF8-B mesh:allowableQualifier jvr:-XV06LPML-W, jvr:-THHNVC7V-3, jvr:-NB0XHT3S-N, jvr:-NKM836P1-M, jvr:-SBNWSM1T-R, jvr:-G7KXQWSR-5, jvr:-WK5F724J-1, jvr:-Z9TSGBXH-4, jvr:-CB30NGKB-3, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-S0CS1X5R-5, jvr:-NHL3D2X0-S, jvr:-H7K65Q8S-Z, jvr:-NFTHND7Q-8, jvr:-HQRFT0C6-B, jvr:-BT300B3G-Q, jvr:-FWD2BGQ0-9, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-TJHVZCRZ-0, jvr:-Q3979798-W, jvr:-L6C0XPHT-4, jvr:-G4R176S9-J, jvr:-R0ZCQ8X6-J, jvr:-D0F21513-5, jvr:-G30ZJ446-J ; skos:hiddenLabel "Nicotine Bitartrate"@en, "Bitartrate de nicotine"@fr, "Nicotine Tartrate"@en ; a mesh:Descriptor, skos:Concept ; skos:altLabel "R7M676M8YV"@en, "R7M676M8YV"@fr, "6M3C89ZY6R"@en, "6M3C89ZY6R"@fr, "Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-"@fr, "Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-"@en, "54-11-5"@fr, "54-11-5"@en ; mesh:pharmacologicalAction jvr:-CVGP4GCW-J, jvr:-TKJ6KRDN-X, jvr:-WHJGX3HF-L ; skos:inScheme jvr: ; owl:sameAs ; skos:broader jvr:-P551XG36-F, jvr:-RKLTD9PC-N ; skos:related jvr:-MW24N812-V ; dc:created "1999-01-01"^^xsd:date ; dc:modified "2018-04-10"^^xsd:date ; dc:established "1966-01-01"^^xsd:date ; skos:definition "Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke."@en ; skos:prefLabel "Nicotine"@fr, "Nicotine"@en . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-CVGP4GCW-J skos:prefLabel "Ganglionic Stimulants"@en, "Gangliostimulants"@fr ; a mesh:Descriptor, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-MW24N812-V skos:prefLabel "Tabac"@fr, "Tobacco"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-ZB2RQRF8-B . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-P551XG36-F skos:prefLabel "Pyridines"@fr, "Pyridines"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZB2RQRF8-B . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-RKLTD9PC-N skos:prefLabel "Alcaloïdes des Solanaceae"@fr, "Solanaceous Alkaloids"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-ZB2RQRF8-B . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WHJGX3HF-L skos:prefLabel "Smoking Cessation Agents"@en, "Agents de sevrage tabagique"@fr ; a mesh:Descriptor, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TKJ6KRDN-X skos:prefLabel "Agonistes nicotiniques"@fr, "Nicotinic Agonists"@en ; a mesh:Descriptor, skos:Concept .