@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HT9K36DZ-K skos:prefLabel "Type I site-specific deoxyribonuclease"@fr, "Deoxyribonucleases, Type I Site-Specific"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-XT3C2LT7-0 . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XT3C2LT7-0 mesh:allowableQualifier jvr:-G7KXQWSR-5, jvr:-XV06LPML-W, jvr:-WZF2ZR3L-B, jvr:-NKM836P1-M, jvr:-THHNVC7V-3, jvr:-NB0XHT3S-N, jvr:-S0CS1X5R-5, jvr:-Q3979798-W, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-SBNWSM1T-R, jvr:-T2TS0S41-N, jvr:-N2WP45CN-V, jvr:-CJXMKG5Q-F, jvr:-NFTHND7Q-8, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-W6SQV79N-S, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-BT300B3G-Q, jvr:-CB30NGKB-3, jvr:-M63HSDM7-1, jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-NHL3D2X0-S, jvr:-WK5F724J-1, jvr:-HQRFT0C6-B, jvr:-L6C0XPHT-4 ; skos:inScheme jvr: ; skos:altLabel "Enzyme de restriction de l'ADN"@fr, "Restriction Endonuclease"@en, "Restriction Endonucleases"@en, "ADN endonucléase"@fr, "Enzyme de restriction"@fr, "DNA Restriction Enzyme"@en ; skos:hiddenLabel "EC 3.1.21.-"@fr, "EC 3.1.21.-"@en ; skos:definition "Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1."@en ; owl:sameAs ; skos:prefLabel "DNA restriction enzymes"@fr, "DNA Restriction Enzymes"@en ; skos:broader jvr:-MKBRFG3D-P, jvr:-C15MGKVK-S ; dc:created "1974-11-19"^^xsd:date ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-HT9K36DZ-K, jvr:-MP38TRHT-B, jvr:-M9GGHCJ3-Q ; skos:related jvr:-XW08LNJC-G, jvr:-NGBS5G2J-5 ; dc:established "1978-01-01"^^xsd:date ; dc:modified "2006-07-05"^^xsd:date ; mesh:registryNumber "EC 3.1.21.-" . jvr:-M9GGHCJ3-Q skos:prefLabel "Deoxyribonucleases, Type II Site-Specific"@en, "Type II site-specific deoxyribonuclease"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-XT3C2LT7-0 . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-C15MGKVK-S skos:prefLabel "Enzymes de restriction-modification de l'ADN"@fr, "DNA Restriction-Modification Enzymes"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XT3C2LT7-0 . jvr:-MP38TRHT-B skos:prefLabel "Type III site-specific deoxyribonuclease"@fr, "Deoxyribonucleases, Type III Site-Specific"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-XT3C2LT7-0 . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-MKBRFG3D-P skos:prefLabel "Endodeoxyribonucleases"@fr, "Endodeoxyribonucleases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XT3C2LT7-0 . jvr:-NGBS5G2J-5 skos:prefLabel "Polymorphisme de restriction"@fr, "Polymorphism, Restriction Fragment Length"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-XT3C2LT7-0 . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XW08LNJC-G skos:prefLabel "Cartographie de restriction"@fr, "Restriction Mapping"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-XT3C2LT7-0 . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .