@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-V8B160F9-Z mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-RKGZF8PT-H
  skos:prefLabel "Antidépresseurs"@fr, "Antidepressive Agents"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-XR0VST6Z-2 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-V919KX05-J mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-VVKKLXFF-N
  skos:prefLabel "Adrenergic Uptake Inhibitors"@en, "Inhibiteurs de la capture adrénergique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-XR0VST6Z-2 .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q0V3B6NN-L mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-B92JTH6C-R mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-XWC4T4KF-R mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-ZBTMLMK4-H mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-Z4BQ5GQ2-G mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M76WWR0L-6 mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R71MKQ38-X mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FTH7TVRN-L mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DPTC0HPM-Q mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LXJFNVPL-1 mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XR0VST6Z-2
  mesh:allowableQualifier jvr:-FWD2BGQ0-9, jvr:-BT300B3G-Q, jvr:-T9HQD7ST-J, jvr:-W6SQV79N-S, jvr:-NFTHND7Q-8, jvr:-HQRFT0C6-B, jvr:-NB0XHT3S-N, jvr:-CB30NGKB-3, jvr:-SBNWSM1T-R, jvr:-H7K65Q8S-Z, jvr:-THHNVC7V-3, jvr:-WK5F724J-1, jvr:-S0CS1X5R-5, jvr:-NHL3D2X0-S, jvr:-G30ZJ446-J, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-XV06LPML-W, jvr:-D0F21513-5, jvr:-L6C0XPHT-4, jvr:-R3QWLHRG-V, jvr:-Q3979798-W ;
  dc:modified "2021-06-30"^^xsd:date ;
  skos:altLabel "Tricyclic Antidepressant"@en, "Tricyclic Antidepressive Agents"@en, "Antidepressants, Tricyclic"@en, "Tricyclic Antidepressive Agent"@en, "Antidepressant Drugs, Tricyclic"@en, "Médicaments antidépresseurs tricycliques"@fr, "Tricyclic Antidepressant Drug"@en ;
  dc:established "1975-09-01"^^xsd:date ;
  skos:related jvr:-VVKKLXFF-N ;
  skos:definition "Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system."@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RKGZF8PT-H ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000929> ;
  skos:inScheme jvr: ;
  skos:prefLabel "Antidépresseurs tricycliques"@fr, "Antidepressive Agents, Tricyclic"@en ;
  dc:created "1974-11-11"^^xsd:date .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-MHLLX565-7 mesh:pharmacologicalAction jvr:-XR0VST6Z-2 .
jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .