@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-FLHQL1FV-7
  skos:prefLabel "Immunoprotéines"@fr, "Immunoproteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-XNZ0F4HK-5 .

jvr:-ZVZ6LL0Z-Q
  skos:prefLabel "Sous-unités des immunoglobulines"@fr, "Immunoglobulin Subunits"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-JPND5MN7-P
  skos:prefLabel "Gènes d'immunoglobuline"@fr, "Genes, Immunoglobulin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-XNZ0F4HK-5 .

jvr:-XNZ0F4HK-5
  mesh:allowableQualifier jvr:-S0CS1X5R-5, jvr:-CJXMKG5Q-F, jvr:-WZF2ZR3L-B, jvr:-Q3979798-W, jvr:-XV06LPML-W, jvr:-NKM836P1-M, jvr:-NB0XHT3S-N, jvr:-L6C0XPHT-4, jvr:-CB30NGKB-3, jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R, jvr:-T2TS0S41-N, jvr:-G7KXQWSR-5, jvr:-Z9TSGBXH-4, jvr:-NFTHND7Q-8, jvr:-FWD2BGQ0-9, jvr:-W6SQV79N-S, jvr:-H7K65Q8S-Z, jvr:-G30ZJ446-J, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-N2WP45CN-V, jvr:-D0F21513-5, jvr:-TJHVZCRZ-0 ;
  skos:inScheme jvr: ;
  skos:broader jvr:-FLHQL1FV-7, jvr:-XL9VCVDB-0 ;
  a mesh:Descriptor, skos:Concept ;
  skos:altLabel "Immune Globulin"@en, "Immunoglobulin"@en, "Immuno-globulines"@fr, "Immune Globulins"@en, "Globulins, Immune"@en ;
  skos:narrower jvr:-SKBQV2H0-3, jvr:-WZ6FZL37-5, jvr:-RTH000RV-7, jvr:-ZL2HV2BR-K, jvr:-K8TXN0VW-X, jvr:-ZVZ6LL0Z-Q, jvr:-DJX3PD7K-Q ;
  dc:created "1999-01-01"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-RBRTJ68X-8 ;
  skos:prefLabel "Immunoglobulines"@fr, "Immunoglobulins"@en ;
  dc:established "1972-01-01"^^xsd:date ;
  dc:modified "2020-05-27"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D007136> ;
  skos:definition "Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses."@en ;
  skos:related jvr:-PHH88QCN-W, jvr:-KK8X6WPG-8, jvr:-JPND5MN7-P .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-KK8X6WPG-8
  skos:prefLabel "Immunité"@fr, "Immunity"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-XNZ0F4HK-5 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-SKBQV2H0-3
  skos:prefLabel "Immunoglobulin Constant Regions"@en, "Régions constantes des immunoglobulines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RBRTJ68X-8
  skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-WZ6FZL37-5
  skos:prefLabel "gamma-Globulins"@en, "Gammaglobulines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PHH88QCN-W
  skos:prefLabel "Paraproteinemias"@en, "Paraprotéinémies"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-XNZ0F4HK-5 .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZL2HV2BR-K
  skos:prefLabel "Receptors, Antigen, B-Cell"@en, "Récepteurs pour l'antigène des lymphocytes B"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-DJX3PD7K-Q
  skos:prefLabel "Paraprotéines"@fr, "Paraproteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-XL9VCVDB-0
  skos:prefLabel "Serum Globulins"@en, "Sérum-globulines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-XNZ0F4HK-5 .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-K8TXN0VW-X
  skos:prefLabel "Anticorps"@fr, "Antibodies"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RTH000RV-7
  skos:prefLabel "Immunoglobulin Fragments"@en, "Fragments d'immunoglobuline"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XNZ0F4HK-5 .