@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZGL5VHG5-9 skos:prefLabel "Tubulin Modulators"@en, "Modulateurs de la polymérisation de la tubuline"@fr ; a mesh:Descriptor, skos:Concept . jvr:-WN4RBMR3-B skos:prefLabel "Étoposide"@fr, "Etoposide"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-XNGT3QH2-X . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZSNM46JS-3 skos:prefLabel "Antinéoplasiques d'origine végétale"@fr, "Antineoplastic Agents, Phytogenic"@en ; a mesh:Descriptor, skos:Concept . jvr:-XNGT3QH2-X mesh:allowableQualifier jvr:-NHL3D2X0-S, jvr:-NFTHND7Q-8, jvr:-NKM836P1-M, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-HQRFT0C6-B, jvr:-L6C0XPHT-4, jvr:-G30ZJ446-J, jvr:-W6SQV79N-S, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-NB0XHT3S-N, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-G4R176S9-J, jvr:-WZF2ZR3L-B, jvr:-G7KXQWSR-5, jvr:-R0ZCQ8X6-J, jvr:-D0F21513-5, jvr:-TJHVZCRZ-0, jvr:-FWD2BGQ0-9, jvr:-H7K65Q8S-Z, jvr:-Q3979798-W, jvr:-THHNVC7V-3, jvr:-M63HSDM7-1, jvr:-BT300B3G-Q ; dc:created "1999-01-01"^^xsd:date ; skos:altLabel "477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer)"@fr, "477-47-4 ((5R-(5 alpha,5a alpha,8a alpha,9 alpha))-isomer)"@en, "4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer)"@en, "4375-07-9 ((5R-(5 alpha,5a beta,8a alpha,9 beta))-isomer)"@fr, "4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer)"@fr, "4375-06-8 ((5R-(5 alpha,5a alpha,8a alpha,9 beta))-isomer)"@en, "518-28-5 (Podophyllotoxin)"@fr, "518-28-5 (Podophyllotoxin)"@en, "Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-"@fr, "Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-"@en, "L36H50F353"@fr, "L36H50F353"@en, "Podofilox"@en, "55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer)"@fr, "55568-79-1 ((5R-(5 alpha,5a alpha,8a beta,9 alpha))-isomer)"@en ; skos:inScheme jvr: ; mesh:pharmacologicalAction jvr:-M2SMNF4X-1, jvr:-ZGL5VHG5-9, jvr:-ZSNM46JS-3 ; skos:hiddenLabel "Podocon-25"@en, "Podofilm"@en, "Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 alpha))-Isomer"@en, "Condyline"@en, "Podophyllotoxin, (5R-(5 alpha,5a alpha,8a alpha,9 beta))-Isomer"@en, "Epipodophyllotoxin"@en, "Warticon"@en, "Podophyllotoxin, (5R-(5 alpha,5a beta,8a alpha,9 beta))-Isomer"@en, "Podophyllotoxin, (5R-(5 alpha,5a alpha,8a beta,9 alpha))-Isomer"@en, "Condylox"@en, "CPH86"@en, "Épipodophyllotoxine"@fr, "Wartec"@en ; skos:broader jvr:-XHNPKHBJ-5, jvr:-LM729JW2-C ; skos:prefLabel "Podophyllotoxine"@fr, "Podophyllotoxin"@en ; a mesh:Descriptor, skos:Concept ; owl:sameAs ; skos:narrower jvr:-WN4RBMR3-B ; dc:established "1973-01-01"^^xsd:date ; skos:definition "A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives."@en ; dc:modified "2016-07-01"^^xsd:date . jvr:-M2SMNF4X-1 skos:prefLabel "Kératolytiques"@fr, "Keratolytic Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-LM729JW2-C skos:prefLabel "Lignans"@en, "Lignanes"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XNGT3QH2-X . jvr:-XHNPKHBJ-5 skos:prefLabel "Tetrahydronaphthalenes"@en, "1,2,3,4-Tétrahydro-naphtalènes"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XNGT3QH2-X . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .