@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XMFHL5FT-6 mesh:allowableQualifier jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-WK5F724J-1, jvr:-N2WP45CN-V, jvr:-Z9TSGBXH-4, jvr:-NHL3D2X0-S, jvr:-CJXMKG5Q-F, jvr:-THHNVC7V-3, jvr:-HQRFT0C6-B, jvr:-SBNWSM1T-R, jvr:-NFTHND7Q-8, jvr:-G30ZJ446-J, jvr:-T9HQD7ST-J, jvr:-XV06LPML-W, jvr:-W6SQV79N-S, jvr:-NKM836P1-M, jvr:-WZF2ZR3L-B, jvr:-G7KXQWSR-5, jvr:-BT300B3G-Q, jvr:-T2TS0S41-N, jvr:-Q3979798-W, jvr:-FWD2BGQ0-9, jvr:-D0F21513-5, jvr:-L6C0XPHT-4, jvr:-S0CS1X5R-5, jvr:-CB30NGKB-3, jvr:-R3QWLHRG-V, jvr:-M63HSDM7-1, jvr:-NB0XHT3S-N ; dc:created "2017-07-11"^^xsd:date ; skos:prefLabel "COP9 Signalosome Complex"@en, "Complexe du signalosome COP9"@fr ; skos:altLabel "Signalsome-9 de la photomorphogèse constitutive"@fr, "Signalsome COP9"@fr, "COP9 Signalsome"@en, "Constitutive Photomorphogenesis 9 Signalosome"@en, "Signalosome COP9"@fr, "COP9 Signalosome (CSN)"@en, "Constitutive Photomorphogenesis 9 Signalsome"@en, "Signalosome-9 de la photomorphogèse constitutive"@fr, "Signalosome COP9 (CSN)"@fr ; a mesh:Descriptor, skos:Concept ; mesh:registryNumber "EC 3.4.19.12" ; skos:hiddenLabel "Sous-unité 7A du signalosome COP9"@fr, "EC 3.4.19.12"@fr, "EC 3.4.19.12"@en, "COP9 Signalosome Subunit 7A"@en, "Sgn3"@fr, "Sgn3"@en, "Sous-unité 2 du signalosome COP9"@fr, "Sous-unité 6 du signalosome COP9"@fr, "COP9 Signalosome Subunit 1"@en, "FUSCA Protein 11"@en, "COP9 Signalosome Subunit 4"@en, "COP9 Signalosome Subunit 7B"@en, "Sous-unité 1 du signalosome COP9"@fr, "COP9 Signalosome Subunit 5"@en, "Sous-unité 8 du signalosome COP9"@fr, "Signalosome Subunit 3"@en, "COP9 Signalosome Subunit 8"@en, "COP9 Signalosome Subunit 2"@en, "Sous-unité 4 du signalosome COP9"@fr, "Suppresseur-1 de la voie des protéines G"@fr, "Protéine FUSCA11"@fr, "COP9 Signalosome Subunit 6"@en, "Sous-unité 3 du signalosome COP9"@fr, "G Protein Pathway Suppressor 1"@en, "Sous-unité 5 du signalosome COP9"@fr, "Sous-unité 7B du signalosome COP9"@fr, "COP9 Signalosome Subunit 3"@en ; owl:sameAs ; skos:broader jvr:-D41C6KX8-9, jvr:-DLZR6K0K-H ; skos:definition "A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits (CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where it controls gene transcription in response to light."@en ; skos:inScheme jvr: ; dc:established "2018-01-01"^^xsd:date ; dc:modified "2017-06-29"^^xsd:date . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-DLZR6K0K-H skos:prefLabel "Ubiquitin-specific proteases"@fr, "Ubiquitin-Specific Proteases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XMFHL5FT-6 . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-D41C6KX8-9 skos:prefLabel "Multiprotein Complexes"@en, "Complexes multiprotéiques"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-XMFHL5FT-6 . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .