@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-S4N4T46V-W
  skos:prefLabel "Vinorelbine"@fr, "Vinorelbine"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XFSJ5C0J-M .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZGL5VHG5-9
  skos:prefLabel "Tubulin Modulators"@en, "Modulateurs de la polymérisation de la tubuline"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-VTVNKZWP-B
  skos:prefLabel "Antinéoplasiques"@fr, "Antineoplastic Agents"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N6CQML7N-T
  skos:prefLabel "Alcaloïdes formés par condensation de sécologanine et de tryptamine"@fr, "Secologanin Tryptamine Alkaloids"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-XFSJ5C0J-M .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-B1MDS1BZ-5
  skos:prefLabel "Vindésine"@fr, "Vindesine"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XFSJ5C0J-M .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-SJTQ96MZ-5
  skos:prefLabel "Vincamine"@fr, "Vincamine"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XFSJ5C0J-M .

jvr:-RJ89R1CP-1
  skos:prefLabel "Vinblastine"@fr, "Vinblastine"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XFSJ5C0J-M .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-WGWK2HFQ-1
  skos:prefLabel "Vincristine"@fr, "Vincristine"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-XFSJ5C0J-M .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-XFSJ5C0J-M
  mesh:allowableQualifier jvr:-NFTHND7Q-8, jvr:-T9HQD7ST-J, jvr:-NKM836P1-M, jvr:-THHNVC7V-3, jvr:-WK5F724J-1, jvr:-R0ZCQ8X6-J, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-Q3979798-W, jvr:-W6SQV79N-S, jvr:-H7K65Q8S-Z, jvr:-BT300B3G-Q, jvr:-L6C0XPHT-4, jvr:-D0F21513-5, jvr:-NB0XHT3S-N, jvr:-NHL3D2X0-S, jvr:-TJHVZCRZ-0, jvr:-G7KXQWSR-5, jvr:-CB30NGKB-3, jvr:-R3QWLHRG-V, jvr:-M63HSDM7-1, jvr:-SBNWSM1T-R, jvr:-HQRFT0C6-B, jvr:-XV06LPML-W, jvr:-S0CS1X5R-5 ;
  dc:modified "2020-05-27"^^xsd:date ;
  skos:narrower jvr:-B1MDS1BZ-5, jvr:-SJTQ96MZ-5, jvr:-S4N4T46V-W, jvr:-WGWK2HFQ-1, jvr:-RJ89R1CP-1 ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D014748> ;
  dc:created "1999-01-01"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-ZGL5VHG5-9, jvr:-VTVNKZWP-B ;
  a skos:Concept, mesh:Descriptor ;
  skos:altLabel "Alcaloïdes de pervenche"@fr ;
  skos:broader jvr:-N6CQML7N-T ;
  skos:prefLabel "Vinca Alkaloids"@en, "Alcaloïdes de Vinca"@fr ;
  skos:inScheme jvr: ;
  skos:definition "A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS."@en ;
  dc:established "1973-01-01"^^xsd:date .