@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-DZ4SSWKN-M
  skos:prefLabel "CD11c Antigen"@en, "Antigènes CD11c"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-X5X803P5-Z
  skos:narrower jvr:-K7GQ464Q-1, jvr:-DZ4SSWKN-M, jvr:-SQ72BJBF-W, jvr:-MM92BZSJ-D, jvr:-WHJV50DZ-B, jvr:-Q8XM3QXC-Z, jvr:-C4ZR9GWB-V, jvr:-WGHWG87L-9, jvr:-PP3KG4XC-8, jvr:-JFQ5VLPT-R, jvr:-CT7BB1JQ-J ;
  a mesh:Descriptor, skos:Concept ;
  mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-N2WP45CN-V, jvr:-SBNWSM1T-R, jvr:-L6C0XPHT-4, jvr:-FWD2BGQ0-9, jvr:-TJHVZCRZ-0, jvr:-CJXMKG5Q-F, jvr:-H7K65Q8S-Z, jvr:-HQRFT0C6-B, jvr:-M63HSDM7-1, jvr:-NHL3D2X0-S, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-G7KXQWSR-5, jvr:-Q3979798-W, jvr:-S0CS1X5R-5, jvr:-WZF2ZR3L-B, jvr:-R0ZCQ8X6-J, jvr:-T2TS0S41-N ;
  skos:altLabel "Chaines alpha des intégrines"@fr, "Integrin alpha Subunits"@en, "Chaînes alpha des intégrines"@fr, "alpha Integrins"@en, "Sous-unités alpha des intégrines"@fr ;
  skos:prefLabel "Intégrines alpha"@fr, "Integrin alpha Chains"@en ;
  dc:modified "2013-07-09"^^xsd:date ;
  skos:broader jvr:-JR6SVVC4-1 ;
  skos:inScheme jvr: ;
  skos:definition "The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4."@en ;
  dc:created "2002-07-02"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D039001> ;
  dc:established "2003-01-01"^^xsd:date .

jvr:-Q8XM3QXC-Z
  skos:prefLabel "Intégrine alpha3"@fr, "Integrin alpha3"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-JFQ5VLPT-R
  skos:prefLabel "Antigènes CD11a"@fr, "CD11a Antigen"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-SQ72BJBF-W
  skos:prefLabel "Intégrine alpha5"@fr, "Integrin alpha5"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MM92BZSJ-D
  skos:prefLabel "Intégrine alpha2"@fr, "Integrin alpha2"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-PP3KG4XC-8
  skos:prefLabel "Integrin alpha4"@en, "Intégrine alpha4"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-C4ZR9GWB-V
  skos:prefLabel "Intégrine alpha1"@fr, "Integrin alpha1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-K7GQ464Q-1
  skos:prefLabel "Integrin alpha6"@en, "Intégrine alpha6"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-JR6SVVC4-1
  skos:prefLabel "Intégrines"@fr, "Integrins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-X5X803P5-Z .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CT7BB1JQ-J
  skos:prefLabel "Intégrine alphaV"@fr, "Integrin alphaV"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WGHWG87L-9
  skos:prefLabel "CD11b Antigen"@en, "Antigènes CD11b"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-WHJV50DZ-B
  skos:prefLabel "Glycoprotéine-IIb de membrane plaquettaire"@fr, "Platelet Membrane Glycoprotein IIb"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-X5X803P5-Z .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .