@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-VNHV7NS6-J
  skos:prefLabel "Antigènes mineurs d'histocompatibilité"@fr, "Minor Histocompatibility Antigens"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-X1NBGFSG-L .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-CVCBN1XG-B
  skos:prefLabel "Trastuzumab"@fr, "Trastuzumab"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-X1NBGFSG-L .

jvr:-X1NBGFSG-L
  skos:altLabel "Erb-b2 Receptor Tyrosine Kinases"@en, "Protéine p185(c-neu)"@fr, "Antigène CD340"@fr, "p185erbB2 Protein"@en, "Protéine du proto-oncogène HER-2"@fr, "Tyrosine Kinase-type Cell Surface Receptor HER2"@en, "Neu Receptor"@en, "Proto-Oncogene Protein p185(neu)"@en, "Récepteur neu"@fr, "Protéine du proto-oncogène erbB-2"@fr, "Récepteur erbB-2"@fr, "Protéines proto-oncogènes c-erbB-2"@fr, "erbB-2 Receptor Protein-Tyrosine Kinase"@en, "Protéine oncogène HER-2"@fr, "Protéine proto-oncogène neu"@fr, "Proto-oncogene Protein Neu"@en, "Oncogene Protein HER-2"@en, "Metastatic Lymph Node Gene 19 Protein"@en, "Proto-Oncogene Protein HER-2"@en, "Proto-oncogène c-ErbB-2"@fr, "Proto-Oncogene Proteins c-erbB-2"@en, "Receptors, erbB-2"@en, "Antigens, CD340"@en, "c-erbB-2 Protein"@en, "Protéine p185(erbB2)"@fr, "p185(c-neu)"@fr, "p185(c-neu)"@en, "Protéine du proto-oncogène neu"@fr, "Protéine proto-oncogène p185(neu)"@fr, "CD340 Antigen"@en, "Receptor, Neu"@en, "Protéine c-erbB-2"@fr, "CD340"@fr, "HER-2 Proto-Oncogene Protein"@en, "neu Proto-Oncogene Protein"@en, "erbB-2 Proto-Oncogene Protein"@en, "Protéine proto-oncogène HER-2"@fr ;
  dc:created "1999-11-04"^^xsd:date ;
  skos:broader jvr:-VNHV7NS6-J, jvr:-T7604J8V-K, jvr:-NN0FP8FS-8, jvr:-Q3XVSMGH-8 ;
  mesh:registryNumber "EC 2.7.10.1" ;
  mesh:allowableQualifier jvr:-NHL3D2X0-S, jvr:-T2TS0S41-N, jvr:-TJHVZCRZ-0, jvr:-Z9TSGBXH-4, jvr:-S0CS1X5R-5, jvr:-M63HSDM7-1, jvr:-CJXMKG5Q-F, jvr:-N2WP45CN-V, jvr:-Q3979798-W, jvr:-D0F21513-5, jvr:-HQRFT0C6-B, jvr:-H7K65Q8S-Z, jvr:-L6C0XPHT-4, jvr:-SBNWSM1T-R, jvr:-FWD2BGQ0-9, jvr:-W6SQV79N-S, jvr:-R0ZCQ8X6-J, jvr:-WZF2ZR3L-B, jvr:-G7KXQWSR-5 ;
  skos:inScheme jvr: ;
  dc:modified "2021-06-21"^^xsd:date ;
  skos:prefLabel "Récepteur ErbB-2"@fr, "Receptor, ErbB-2"@en ;
  a mesh:Descriptor, skos:Concept ;
  dc:established "1995-01-01"^^xsd:date ;
  skos:definition "A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member."@en ;
  skos:related jvr:-Z3RC22R0-1, jvr:-CVCBN1XG-B, jvr:-J3CX065L-Q ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D018719> ;
  skos:hiddenLabel "EC 2.7.10.1"@en, "EC 2.7.10.1"@fr .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T7604J8V-K
  skos:prefLabel "Protéines proto-oncogènes"@fr, "Proto-Oncogene Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-X1NBGFSG-L .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-J3CX065L-Q
  skos:prefLabel "Neuregulins"@en, "Neurégulines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-X1NBGFSG-L .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z3RC22R0-1
  skos:prefLabel "Genes, erbB-2"@en, "Gènes erbB-2"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-X1NBGFSG-L .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NN0FP8FS-8
  skos:prefLabel "Marqueurs biologiques tumoraux"@fr, "Biomarkers, Tumor"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-X1NBGFSG-L .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3XVSMGH-8
  skos:prefLabel "Récepteurs ErbB"@fr, "ErbB Receptors"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-X1NBGFSG-L .