@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NT58TNXQ-G
  skos:prefLabel "Trinucleotide Repeat Expansion"@en, "Expansion de trinucléotide répété"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-VWVSVF45-N .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-KZK3R3W2-V
  skos:prefLabel "Fragile X Syndrome"@en, "Syndrome du chromosome X fragile"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-VWVSVF45-N .

jvr:-MLKJS7X2-4
  skos:prefLabel "DNA Sequence, Unstable"@en, "Séquence instable d'ADN"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-VWVSVF45-N .

jvr:-PPKJKFKK-V
  skos:prefLabel "ethics (Qualifier)"@en, "éthique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CGT2SN12-T
  skos:prefLabel "Chromosome Fragility"@en, "Fragilité des chromosomes"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-VWVSVF45-N .

jvr:-MLD02K7C-B
  skos:prefLabel "Expansion de séquence répétée de l'ADN"@fr, "DNA Repeat Expansion"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-VWVSVF45-N .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-VWVSVF45-N
  skos:inScheme jvr: ;
  dc:established "2004-01-01"^^xsd:date ;
  dc:created "2003-07-09"^^xsd:date ;
  mesh:allowableQualifier jvr:-WZF2ZR3L-B, jvr:-Z9TSGBXH-4, jvr:-N2WP45CN-V, jvr:-PPKJKFKK-V, jvr:-S0CS1X5R-5, jvr:-H7K65Q8S-Z ;
  skos:related jvr:-KZK3R3W2-V, jvr:-NT58TNXQ-G, jvr:-CGT2SN12-T, jvr:-MLD02K7C-B ;
  skos:prefLabel "Sites fragiles de chromosome"@fr, "Chromosome Fragile Sites"@en ;
  a skos:Concept, mesh:Descriptor ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D043283> ;
  skos:broader jvr:-MLKJS7X2-4 ;
  dc:modified "2013-07-09"^^xsd:date ;
  skos:definition "Specific loci that show up during KARYOTYPING as a gap (an uncondensed stretch in closer views) on a CHROMATID arm after culturing cells under specific conditions. These sites are associated with an increase in CHROMOSOME FRAGILITY. They are classified as common or rare, and by the specific culture conditions under which they develop. Fragile site loci are named by the letters \"FRA\" followed by a designation for the specific chromosome, and a letter which refers to which fragile site of that chromosome (e.g. FRAXA refers to fragile site A on the X chromosome. It is a rare, folic acid-sensitive fragile site associated with FRAGILE X SYNDROME.)"@en ;
  skos:altLabel "Fragile Sites, Chromosome"@en .

