@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-VJW0RSPG-W
  skos:definition "A diarylpyrimidine derivative and REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 that is used in the treatment of HIV INFECTIONS. It is also used in combination with other ANTI-HIV AGENTS, since ANTIVIRAL DRUG RESISTANCE emerges rapidly when it is used alone."@en ;
  skos:altLabel "FI96A8X663"@fr, "FI96A8X663"@en, "212WAX8KDD"@fr, "212WAX8KDD"@en, "500287-72-9"@en, "500287-72-9"@fr ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000068696> ;
  mesh:allowableQualifier jvr:-CB30NGKB-3, jvr:-R0ZCQ8X6-J, jvr:-FWD2BGQ0-9, jvr:-THHNVC7V-3, jvr:-HQRFT0C6-B, jvr:-G30ZJ446-J, jvr:-H7K65Q8S-Z, jvr:-NFTHND7Q-8, jvr:-G4R176S9-J, jvr:-R3QWLHRG-V, jvr:-L6C0XPHT-4, jvr:-NHL3D2X0-S, jvr:-Q3979798-W, jvr:-W6SQV79N-S, jvr:-S0CS1X5R-5, jvr:-NKM836P1-M, jvr:-SBNWSM1T-R, jvr:-T9HQD7ST-J, jvr:-M63HSDM7-1, jvr:-TJHVZCRZ-0, jvr:-D0F21513-5, jvr:-XV06LPML-W, jvr:-BT300B3G-Q, jvr:-WK5F724J-1, jvr:-NB0XHT3S-N ;
  skos:hiddenLabel "TMC 278"@en, "R-278474"@fr, "R278474"@fr, "R278474"@en, "Chlorhydrate de rilpivirine"@fr, "Rilpivirine Hydrochloride"@en, "TMC-278"@fr, "TMC-278"@en, "Rilpivirine HCl"@en, "TMC278"@fr, "TMC278"@en ;
  skos:broader jvr:-X9J502WV-F, jvr:-FWBNGBWP-4 ;
  dc:established "2016-01-01"^^xsd:date ;
  skos:narrower jvr:-SMX8TTPV-X ;
  a mesh:Descriptor, skos:Concept ;
  dc:created "2015-07-01"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-HKVQ0KFW-S, jvr:-TJ580XM9-W ;
  dc:modified "2016-05-31"^^xsd:date ;
  skos:prefLabel "Rilpivirine"@en, "Rilpivirine"@fr ;
  skos:inScheme jvr: .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-X9J502WV-F
  skos:prefLabel "Nitriles"@fr, "Nitriles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-VJW0RSPG-W .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJ580XM9-W
  skos:prefLabel "Anti-HIV Agents"@en, "Agents antiVIH"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWBNGBWP-4
  skos:prefLabel "Pyrimidines"@fr, "Pyrimidines"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-VJW0RSPG-W .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SMX8TTPV-X
  skos:prefLabel "Emtricitabine, Rilpivirine, Tenofovir Drug Combination"@en, "Association d'emtricitabine, de rilpivirine et de ténofovir"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-VJW0RSPG-W .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HKVQ0KFW-S
  skos:prefLabel "Inhibiteurs de la transcriptase inverse"@fr, "Reverse Transcriptase Inhibitors"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .