@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-FGXV9PT8-9 skos:prefLabel "Antinematodal Agents"@en, "Antihelminthiques antinématodes"@fr ; a mesh:Descriptor, skos:Concept . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-VTVNKZWP-B skos:prefLabel "Antinéoplasiques"@fr, "Antineoplastic Agents"@en ; a mesh:Descriptor, skos:Concept . jvr:-VGPQWPSZ-V skos:hiddenLabel "Suramin, Hexasodium Salt"@en, "Naganol"@en, "Naganin"@en, "Moranil"@en, "Suramin Sodium"@en, "Naphuride"@en, "Suramine de sodium"@fr, "Suramin, Monosodium Salt"@en, "Suramine sodique"@fr, "Germanin"@en ; dc:modified "2013-07-08"^^xsd:date ; a mesh:Descriptor, skos:Concept ; skos:altLabel "1,3,5-Naphthalenetrisulfonic acid, 8,8'-(carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-"@fr, "1,3,5-Naphthalenetrisulfonic acid, 8,8'-(carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-"@en, "89521262IH"@fr, "89521262IH"@en, "3308-30-3 (mono-Na salt)"@fr, "3308-30-3 (mono-Na salt)"@en, "6032D45BEM"@fr, "6032D45BEM"@en, "129-46-4 (hexa-Na salt)"@fr, "129-46-4 (hexa-Na salt)"@en, "145-63-1 (Suramin)"@en, "145-63-1 (Suramin)"@fr ; mesh:allowableQualifier jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R, jvr:-S0CS1X5R-5, jvr:-G4R176S9-J, jvr:-WK5F724J-1, jvr:-M63HSDM7-1, jvr:-T9HQD7ST-J, jvr:-XV06LPML-W, jvr:-G30ZJ446-J, jvr:-HQRFT0C6-B, jvr:-FWD2BGQ0-9, jvr:-BT300B3G-Q, jvr:-NFTHND7Q-8, jvr:-R0ZCQ8X6-J, jvr:-Q3979798-W, jvr:-W6SQV79N-S, jvr:-CB30NGKB-3, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-TJHVZCRZ-0, jvr:-L6C0XPHT-4, jvr:-H7K65Q8S-Z, jvr:-R3QWLHRG-V, jvr:-THHNVC7V-3, jvr:-NKM836P1-M ; mesh:pharmacologicalAction jvr:-FGXV9PT8-9, jvr:-VTVNKZWP-B, jvr:-KB64SMLN-P ; owl:sameAs ; dc:established "1966-01-01"^^xsd:date ; skos:prefLabel "Suramin"@en, "Suramine"@fr ; skos:broader jvr:-LDR0FDTZ-T ; dc:created "1999-01-01"^^xsd:date ; skos:inScheme jvr: ; skos:definition "A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties."@en . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-LDR0FDTZ-T skos:prefLabel "Naphthalenesulfonates"@en, "Naphtalènesulfonates"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-VGPQWPSZ-V . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KB64SMLN-P skos:prefLabel "Trypanocidal Agents"@en, "Trypanocides"@fr ; a mesh:Descriptor, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .