@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-DPGGJ64L-N skos:prefLabel "Membrane Proteins"@en, "Protéines membranaires"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-V7TNZF1G-W . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-DBBK11XL-1 skos:prefLabel "Flavoproteins"@en, "Flavoprotéines"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-V7TNZF1G-W . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BXHS92L9-D skos:prefLabel "NADPH Oxidase 4"@fr, "NADPH Oxidase 4"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-V7TNZF1G-W . jvr:-QMSZ59ZS-2 skos:prefLabel "NADPH Oxidase 5"@fr, "NADPH Oxidase 5"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-V7TNZF1G-W . jvr:-WCWMB697-P skos:prefLabel "Granulomatous Disease, Chronic"@en, "Granulomatose septique chronique"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-V7TNZF1G-W . jvr:-X83FWJ5H-C skos:prefLabel "NADPH Oxidase 2"@fr, "NADPH Oxidase 2"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-V7TNZF1G-W . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-F5BHTQMH-R skos:prefLabel "NADPH Oxidase 1"@en, "NADPH Oxidase 1"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-V7TNZF1G-W . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-V7TNZF1G-W dc:modified "2018-06-12"^^xsd:date ; mesh:allowableQualifier jvr:-R3QWLHRG-V, jvr:-L6C0XPHT-4, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-WK5F724J-1, jvr:-T2TS0S41-N, jvr:-M63HSDM7-1, jvr:-CB30NGKB-3, jvr:-N2WP45CN-V, jvr:-SBNWSM1T-R, jvr:-NB0XHT3S-N, jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-G7KXQWSR-5, jvr:-FWD2BGQ0-9, jvr:-NFTHND7Q-8, jvr:-CJXMKG5Q-F, jvr:-W6SQV79N-S, jvr:-D0F21513-5, jvr:-G30ZJ446-J, jvr:-BT300B3G-Q, jvr:-NHL3D2X0-S, jvr:-HQRFT0C6-B, jvr:-T9HQD7ST-J, jvr:-WZF2ZR3L-B, jvr:-THHNVC7V-3, jvr:-S0CS1X5R-5, jvr:-H7K65Q8S-Z, jvr:-Q3979798-W ; skos:inScheme jvr: ; skos:altLabel "Nox Proteins"@en, "NADPH Oxidase"@en, "NAD(P)H Oxidases"@en, "NAD(P)H oxidase"@en ; skos:narrower jvr:-QMSZ59ZS-2, jvr:-X83FWJ5H-C, jvr:-TLST4XDG-K, jvr:-BXHS92L9-D, jvr:-F5BHTQMH-R ; skos:hiddenLabel "EC 1.6.3.-"@fr, "EC 1.6.3.-"@en ; mesh:registryNumber "EC 1.6.3.-" ; skos:prefLabel "NADPH Oxidases"@en, "NADPH oxidase"@fr ; a mesh:Descriptor, skos:Concept ; dc:established "1997-01-01"^^xsd:date ; skos:broader jvr:-J74TTJBP-1, jvr:-DPGGJ64L-N, jvr:-DBBK11XL-1 ; owl:sameAs ; dc:created "1996-06-10"^^xsd:date ; skos:definition "A family of membrane-associated flavoprotein NADPH-dependent oxidoreductases that catalyze the univalent reduction of OXYGEN to create SUPEROXIDES. Structurally, they are characterized by six N-terminal transmembrane ALPHA-HELICES, a FLAVIN-ADENINE DINUCLEOTIDE (FAD)-binding region, and a C-terminal NADPH-binding region. They are expressed primarily by EPITHELIAL CELLS in gut, kidney, colon, and smooth muscle tissues, as well as GRANULOCYTES and function to transfer electrons across membranes to molecular oxygen. Defects in the production of superoxide ions by some NADPH oxidases result in GRANULOMATOUS DISEASE, CHRONIC."@en ; skos:related jvr:-WCWMB697-P . jvr: a skos:ConceptScheme . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TLST4XDG-K skos:prefLabel "Dual oxydases"@fr, "Dual Oxidases"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-V7TNZF1G-W . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-J74TTJBP-1 skos:prefLabel "NADH, NADPH oxidoreductases"@fr, "NADH, NADPH Oxidoreductases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-V7TNZF1G-W . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .