@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-V2ZX1MFX-3
  mesh:allowableQualifier jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-NB0XHT3S-N, jvr:-G30ZJ446-J, jvr:-Q3979798-W, jvr:-WZF2ZR3L-B, jvr:-XV06LPML-W, jvr:-HQRFT0C6-B, jvr:-T2TS0S41-N, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-BT300B3G-Q, jvr:-G7KXQWSR-5, jvr:-L6C0XPHT-4, jvr:-SBNWSM1T-R, jvr:-N2WP45CN-V, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8, jvr:-NHL3D2X0-S, jvr:-FWD2BGQ0-9, jvr:-W6SQV79N-S, jvr:-CB30NGKB-3 ;
  skos:altLabel "Immunoglobulins, Fab"@en, "Fragment Fab des immunoglobulines"@fr, "Ig Fab Fragments"@en, "Immunoglobulin Fab Fragment"@en, "Immunoglobulins, Fab Fragment"@en, "Fragments Fab d'Ig"@fr, "Fab Fragments"@en, "Fragments Fab"@fr, "Fragments Fab des Ig"@fr, "Fab Fragment"@en, "Fab Immunoglobulin Fragments"@en ;
  dc:created "1999-01-01"^^xsd:date ;
  skos:narrower jvr:-X3LBQBZK-7, jvr:-LX9R772G-6, jvr:-WX56JBDJ-S, jvr:-JKQ1SQKC-9 ;
  mesh:pharmacologicalAction jvr:-RBRTJ68X-8 ;
  a mesh:Descriptor, skos:Concept ;
  skos:definition "Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN."@en ;
  skos:broader jvr:-RTH000RV-7 ;
  skos:prefLabel "Immunoglobulin Fab Fragments"@en, "Fragments Fab d'immunoglobuline"@fr ;
  skos:inScheme jvr: ;
  dc:established "1973-01-01"^^xsd:date ;
  dc:modified "2020-05-27"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D007140> .

jvr:-WX56JBDJ-S
  skos:prefLabel "Région variable d'immunoglobuline"@fr, "Immunoglobulin Variable Region"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-V2ZX1MFX-3 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RBRTJ68X-8
  skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RTH000RV-7
  skos:prefLabel "Immunoglobulin Fragments"@en, "Fragments d'immunoglobuline"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-V2ZX1MFX-3 .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-JKQ1SQKC-9
  skos:prefLabel "Tuftsin"@en, "Tuftsine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-V2ZX1MFX-3 .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-X3LBQBZK-7
  skos:prefLabel "Abciximab"@en, "Abciximab"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-V2ZX1MFX-3 .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-LX9R772G-6
  skos:prefLabel "Certolizumab Pegol"@en, "Certolizumab pégol"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-V2ZX1MFX-3 .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .