@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QXTGJC02-C
  skos:prefLabel "Extinction de l'expression des gènes"@fr, "Gene Silencing"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-SD19LFDC-7 .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CCP907MB-W
  skos:prefLabel "RNA, Small Interfering"@en, "Petit ARN interférent"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-SD19LFDC-7 .

jvr:-SD19LFDC-7
  skos:hiddenLabel "Co-suppression"@fr, "Cosuppression"@fr, "Cosuppression"@en, "Co-Suppression"@en ;
  skos:broader jvr:-QXTGJC02-C ;
  skos:altLabel "RNAi"@en, "Gene Silencing, Post-Transcriptional"@en, "RNA Silencing"@en, "Posttranscriptional Gene Silencing"@en, "Inactivation génique post-transcriptionnelle"@fr, "Extinction des ARN"@fr, "Interférence ARN"@fr, "Inactivation post-transcriptionnelle des gènes"@fr, "Post-Transcriptional Gene Silencing"@en ;
  skos:definition "A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process. Joint gene silencing of extra copies of genes, such as TRANSGENES, along with the original endogenous gene. Cosuppression is induced by the presence of the extra gene copies via mechanisms that are related to RNA INTERFERENCE."@en ;
  dc:established "2003-01-01"^^xsd:date ;
  skos:inScheme jvr: ;
  skos:prefLabel "Interférence par ARN"@fr, "RNA Interference"@en ;
  skos:related jvr:-SWSBWS2L-W, jvr:-CCP907MB-W, jvr:-C8G6MPMR-1, jvr:-G5161T91-7 ;
  dc:created "2002-07-03"^^xsd:date ;
  mesh:allowableQualifier jvr:-H7K65Q8S-Z, jvr:-WZF2ZR3L-B, jvr:-N2WP45CN-V, jvr:-S0CS1X5R-5 ;
  dc:modified "2016-06-17"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D034622> .

jvr: a skos:ConceptScheme .
jvr:-SWSBWS2L-W
  skos:prefLabel "Complexe réprimant l'expression de l'ARN"@fr, "RNA-Induced Silencing Complex"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-SD19LFDC-7 .

jvr:-G5161T91-7
  skos:prefLabel "Antagomirs"@fr, "Antagomirs"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-SD19LFDC-7 .

jvr:-C8G6MPMR-1
  skos:prefLabel "RNAi Therapeutics"@en, "Thérapie par l'interférence par ARN"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-SD19LFDC-7 .