@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MKZNRS2D-M
  skos:prefLabel "Lapatinib"@fr, "Lapatinib"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-WC1RVRK5-1
  skos:prefLabel "Prazosine"@fr, "Prazosin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L7C0GXDV-T
  skos:prefLabel "Trimetrexate"@en, "Trimétrexate"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LXHGRNR3-T
  skos:prefLabel "Géfitinib"@fr, "Gefitinib"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-S7ZHQ0RH-6
  mesh:allowableQualifier jvr:-CB30NGKB-3, jvr:-XV06LPML-W, jvr:-R0ZCQ8X6-J, jvr:-W6SQV79N-S, jvr:-TJHVZCRZ-0, jvr:-NHL3D2X0-S, jvr:-WK5F724J-1, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-D0F21513-5, jvr:-T9HQD7ST-J, jvr:-L6C0XPHT-4, jvr:-Q3979798-W, jvr:-THHNVC7V-3, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-M63HSDM7-1, jvr:-SBNWSM1T-R, jvr:-NB0XHT3S-N, jvr:-NFTHND7Q-8, jvr:-R3QWLHRG-V, jvr:-H7K65Q8S-Z, jvr:-S0CS1X5R-5, jvr:-NKM836P1-M ;
  skos:inScheme jvr: ;
  dc:established "1966-01-01"^^xsd:date ;
  skos:narrower jvr:-WC1RVRK5-1, jvr:-MKZNRS2D-M, jvr:-QKHNKZ1X-C, jvr:-J9FK396B-2, jvr:-L7C0GXDV-T, jvr:-T60LPJ0K-V, jvr:-LXHGRNR3-T, jvr:-C43BCDNW-C, jvr:-P4D51Q77-W ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D011799> ;
  a skos:Concept, mesh:Descriptor ;
  dc:modified "2021-06-30"^^xsd:date ;
  skos:broader jvr:-PJSCX09B-2 ;
  skos:definition "A group of aromatic heterocyclic compounds that contain a bicyclic structure with two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring."@en ;
  dc:created "1999-01-01"^^xsd:date ;
  skos:altLabel "Quinazoline"@en ;
  skos:prefLabel "Quinazolines"@fr, "Quinazolines"@en .

jvr:-QKHNKZ1X-C
  skos:prefLabel "Quinazolinones"@en, "Quinazolinones"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PJSCX09B-2
  skos:prefLabel "Heterocyclic Compounds, 2-Ring"@en, "Composés hétérobicycliques"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-S7ZHQ0RH-6 .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-J9FK396B-2
  skos:prefLabel "Tétrodotoxine"@fr, "Tetrodotoxin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T60LPJ0K-V
  skos:prefLabel "Afatinib"@fr, "Afatinib"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-P4D51Q77-W
  skos:prefLabel "Linagliptine"@fr, "Linagliptin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-C43BCDNW-C
  skos:prefLabel "Erlotinib Hydrochloride"@en, "Chlorhydrate d'erlotinib"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S7ZHQ0RH-6 .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .