@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-S2FN6N83-K
  skos:altLabel "Genotoxin"@en, "Agents mutagènes"@fr, "Mutagen"@en, "Génotoxines"@fr, "Agents génotoxiques"@fr, "Produits mutagènes"@fr, "Genotoxins"@en ;
  mesh:allowableQualifier jvr:-FWD2BGQ0-9, jvr:-HQRFT0C6-B, jvr:-Q3979798-W, jvr:-T9HQD7ST-J, jvr:-WK5F724J-1, jvr:-H7K65Q8S-Z, jvr:-SBNWSM1T-R, jvr:-NFTHND7Q-8, jvr:-TJHVZCRZ-0, jvr:-W6SQV79N-S, jvr:-NB0XHT3S-N, jvr:-G30ZJ446-J, jvr:-D0F21513-5, jvr:-THHNVC7V-3, jvr:-L6C0XPHT-4, jvr:-CB30NGKB-3, jvr:-NKM836P1-M, jvr:-R3QWLHRG-V ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-XQGH99WV-B ;
  dc:established "1966-01-01"^^xsd:date ;
  dc:modified "2020-05-27"^^xsd:date ;
  skos:related jvr:-PCGD0J2R-7, jvr:-Z5N478GX-B, jvr:-CN48R0SN-X, jvr:-CJHX9QH8-6, jvr:-C0K9WRPB-X ;
  skos:prefLabel "Mutagens"@en, "Mutagènes"@fr ;
  skos:hiddenLabel "Clastogènes"@fr, "Agents clastogènes"@fr, "Clastogen"@en, "Clastogens"@en ;
  skos:broader jvr:-S1JFLTH9-3 ;
  dc:created "1999-01-01"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D009153> ;
  skos:inScheme jvr: ;
  skos:definition "Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes."@en .

jvr:-C1JP8JH9-8 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-TBH3J6NL-Q mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-TW6M1R29-D mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-D1MJDKB9-M mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-BDTJQ4G2-1 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-Z5N478GX-B
  skos:prefLabel "Mutation"@fr, "Mutation"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-S2FN6N83-K .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z4W97DZK-0 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-X2TSP78L-B mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-X8B1PCT1-D mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W8762TTR-7 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-NBBWCB3G-6 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FPCLH3LP-7 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-XQGH99WV-B
  skos:prefLabel "Aneugènes"@fr, "Aneugens"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-S2FN6N83-K .

jvr:-CN48R0SN-X
  skos:prefLabel "Adduits à l'ADN"@fr, "DNA Adducts"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-S2FN6N83-K .

jvr:-CJHX9QH8-6
  skos:prefLabel "Cancérogènes"@fr, "Carcinogens"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-S2FN6N83-K .

jvr:-J8SZTG59-V mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-S1JFLTH9-3
  skos:prefLabel "Noxas"@fr, "Noxae"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-S2FN6N83-K .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-PWXNTX4M-Q mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-QTZR120M-0 mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-VKPC4GPK-G mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-C0K9WRPB-X
  skos:prefLabel "Mutagenèse"@fr, "Mutagenesis"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-S2FN6N83-K .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-P69BPHTG-D mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-PMVHFKZV-T mesh:pharmacologicalAction jvr:-S2FN6N83-K .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PCGD0J2R-7
  skos:prefLabel "Agents alcoylants"@fr, "Alkylating Agents"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-S2FN6N83-K .

