@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-F2DPQ7MS-G skos:prefLabel "Proline-Directed Protein Kinases"@en, "Proline-directed protein kinases"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-S25VW0NW-8 . jvr:-HGQ5WG99-3 skos:prefLabel "Kinase-6 cycline-dépendante"@fr, "Cyclin-Dependent Kinase 6"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-MRBZ44KM-J skos:prefLabel "Maturation-Promoting Factor"@en, "Facteur de promotion de la maturation"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-QBVCPWVF-W skos:prefLabel "Kinases CDC2-CDC28"@fr, "CDC2-CDC28 Kinases"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-S25VW0NW-8 mesh:registryNumber "EC 2.7.11.22" ; mesh:allowableQualifier jvr:-WZF2ZR3L-B, jvr:-NFTHND7Q-8, jvr:-R3QWLHRG-V, jvr:-THHNVC7V-3, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-D0F21513-5, jvr:-CB30NGKB-3, jvr:-N2WP45CN-V, jvr:-H7K65Q8S-Z, jvr:-W6SQV79N-S, jvr:-CJXMKG5Q-F, jvr:-HQRFT0C6-B, jvr:-FWD2BGQ0-9, jvr:-NB0XHT3S-N, jvr:-BT300B3G-Q, jvr:-TJHVZCRZ-0, jvr:-L6C0XPHT-4, jvr:-G30ZJ446-J, jvr:-T9HQD7ST-J, jvr:-Q3979798-W, jvr:-M63HSDM7-1, jvr:-NHL3D2X0-S, jvr:-G7KXQWSR-5, jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-T2TS0S41-N, jvr:-NKM836P1-M, jvr:-S0CS1X5R-5 ; skos:altLabel "Protéines CDK"@fr, "cdk Proteins"@en, "CDK (Cyclin-Dependent Kinase)"@fr, "Cyclin-dependent kinase"@fr, "Protéines-kinases cyclines-dépendantes"@fr, "Kinases dépendantes des cyclines"@fr, "Cyclin-Dependent Protein Kinase"@en, "Cyclin-Dependent Protein Kinases"@en, "Cyclin-Dependent Kinase"@en, "Protéines-kinases dépendantes des cyclines"@fr ; skos:inScheme jvr: ; skos:narrower jvr:-MRBZ44KM-J, jvr:-QBVCPWVF-W, jvr:-XV1Z0QQ9-K, jvr:-M0ZZ54NK-7, jvr:-HGQ5WG99-3, jvr:-Z2WMH7RD-S, jvr:-L3FDRLHQ-H ; owl:sameAs ; a mesh:Descriptor, skos:Concept ; skos:prefLabel "Cyclin-Dependent Kinases"@en, "Kinases cyclines-dépendantes"@fr ; skos:broader jvr:-F2DPQ7MS-G, jvr:-JSW5590K-N ; dc:established "1995-01-01"^^xsd:date ; dc:created "1994-05-31"^^xsd:date ; skos:hiddenLabel "EC 2.7.11.22"@fr, "EC 2.7.11.22"@en ; dc:modified "2021-05-21"^^xsd:date ; skos:definition "Protein kinases that control cell cycle progression in all eukaryotes and require physical association with CYCLINS to achieve full enzymatic activity. Cyclin-dependent kinases are regulated by phosphorylation and dephosphorylation events."@en . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-JSW5590K-N skos:prefLabel "Protéines du cycle cellulaire"@fr, "Cell Cycle Proteins"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-S25VW0NW-8 . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L3FDRLHQ-H skos:prefLabel "Cyclin-Dependent Kinase 2"@en, "Kinase-2 cycline-dépendante"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M0ZZ54NK-7 skos:prefLabel "Cyclin-Dependent Kinase 3"@en, "Kinase-3 cycline-dépendante"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XV1Z0QQ9-K skos:prefLabel "Cyclin-Dependent Kinase 8"@en, "Cyclin-Dependent Kinase 8"@fr ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z2WMH7RD-S skos:prefLabel "Kinase-4 cycline-dépendante"@fr, "Cyclin-Dependent Kinase 4"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-S25VW0NW-8 . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .