@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-ZBSVMDHJ-T
  skos:prefLabel "Guanylate Cyclase"@en, "Guanylate cyclase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-QL35BZGZ-C
  skos:prefLabel "Adaptor Proteins, Signal Transducing"@en, "Protéines adaptatrices de la transduction du signal"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-S90X7MF2-N
  skos:prefLabel "GTP-Binding Proteins"@en, "Protéines G"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-MXHMS4X7-Q
  skos:prefLabel "Olfactory Marker Protein"@en, "Protéine marqueur olfactif"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-P2QPF94S-4
  skos:prefLabel "Adenylyl Cyclases"@en, "Adenylate Cyclase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-J1MRT6LV-2
  skos:prefLabel "Homologue-4 de la protéine Disks Large"@fr, "Disks Large Homolog 4 Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CG2RL965-3
  skos:prefLabel "Phosphatidylinositol 3-kinases"@fr, "Phosphatidylinositol 3-Kinases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-LSSHL6LS-D
  skos:prefLabel "Régulateurs des protéines G"@fr, "GTP-Binding Protein Regulators"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-QW1M6C7K-J
  skos:prefLabel "Mitogen-Activated Protein Kinase Phosphatases"@fr, "Mitogen-Activated Protein Kinase Phosphatases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZN52ZLS2-M
  skos:prefLabel "Sirtuins"@en, "Sirtuines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-Q044S4FG-7
  skos:prefLabel "Phosphatidylethanolamine Binding Protein"@en, "Protéine de liaison de phosphatidyl-éthanolamine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-DKWV9S7T-9
  skos:prefLabel "3',5'-Cyclic-GMP Phosphodiesterases"@fr, "3',5'-Cyclic-GMP Phosphodiesterases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-Q8FV865Z-G
  skos:prefLabel "Protéine-3 induite par le facteur de nécrose tumorale alpha"@fr, "Tumor Necrosis Factor alpha-Induced Protein 3"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-FZ2FN7DH-T
  skos:prefLabel "Protéines I-kappa B"@fr, "I-kappa B Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-GLK1B94T-K
  skos:prefLabel "Protéine-1 d'inhibition de croissance"@fr, "Inhibitor of Growth Protein 1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-TP5B7P0H-F
  skos:prefLabel "Protein Serine-Threonine Kinases"@en, "Protein-Serine-Threonine Kinases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-QS0KZ1MV-0
  skos:prefLabel "Facteur de transcription ATF-6"@fr, "Activating Transcription Factor 6"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H40P090J-M
  skos:prefLabel "Protein Tyrosine Phosphatases"@fr, "Protein Tyrosine Phosphatases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SHF8NK8P-C
  skos:prefLabel "Methyl-Accepting Chemotaxis Proteins"@en, "Protéines chimiotactiques accepteuses de méthyle"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G373PN6Q-J
  skos:prefLabel "Protéines régulatrices de l'apoptose"@fr, "Apoptosis Regulatory Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-Q6HBQWJ9-5
  skos:prefLabel "Mésothéline"@fr, "Mesothelin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-P5K3DBDP-J
  skos:prefLabel "Cyclin-Dependent Kinase Inhibitor Proteins"@en, "Protéines inhibitrices des kinases cyclines-dépendantes"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-GB2CPLP0-S
  skos:prefLabel "Protéines associées à SAP90-PSD95"@fr, "SAP90-PSD95 Associated Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PC7B4NHS-1
  skos:prefLabel "Peptides"@fr, "Peptides"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-RZ7ZF59C-G .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PL86W9KB-F
  skos:prefLabel "Protéine tumorale-1 contrôlée par la traduction"@fr, "Tumor Protein, Translationally-Controlled 1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-LNRR67WC-X
  skos:prefLabel "PTEN Phosphohydrolase"@en, "Phosphohydrolase PTEN"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-BMZ0NJLN-K
  skos:prefLabel "Phosphoprotein Phosphatases"@fr, "Phosphoprotein Phosphatases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-VJCWDX35-8
  skos:prefLabel "Protéines et peptides de signalisation du rythme circadien"@fr, "Circadian Rhythm Signaling Peptides and Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-KC9GD4TJ-Z
  skos:prefLabel "Tuberous Sclerosis Complex 2 Protein"@en, "Protéine-2 du complexe de la sclérose tubéreuse"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-MQRWZGD9-T
  skos:prefLabel "NLR Proteins"@en, "Protéines NLR"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-GVJ2JMXS-G
  skos:prefLabel "Cold Shock Proteins and Peptides"@en, "Protéines et peptides de choc froid"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-K2D7SD7B-J
  skos:prefLabel "Protein-Tyrosine Kinases"@en, "Protein-tyrosine kinases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-RZ7ZF59C-G
  skos:narrower jvr:-QL35BZGZ-C, jvr:-Q6HBQWJ9-5, jvr:-MD4CN4SF-H, jvr:-Q044S4FG-7, jvr:-K2D7SD7B-J, jvr:-JCR5Q238-4, jvr:-VJCWDX35-8, jvr:-GVJ2JMXS-G, jvr:-H40P090J-M, jvr:-W43TNHW6-1, jvr:-G373PN6Q-J, jvr:-PL86W9KB-F, jvr:-ZN52ZLS2-M, jvr:-QW1M6C7K-J, jvr:-S90X7MF2-N, jvr:-GLK1B94T-K, jvr:-DKWV9S7T-9, jvr:-CG2RL965-3, jvr:-ZBSVMDHJ-T, jvr:-SHF8NK8P-C, jvr:-MXHMS4X7-Q, jvr:-FZ2FN7DH-T, jvr:-P5K3DBDP-J, jvr:-Q8FV865Z-G, jvr:-LNRR67WC-X, jvr:-QZQDLP50-T, jvr:-QPM1CPT8-5, jvr:-LSSHL6LS-D, jvr:-QS0KZ1MV-0, jvr:-BMZ0NJLN-K, jvr:-P7BBLCJT-3, jvr:-TP5B7P0H-F, jvr:-MRZHSG15-F, jvr:-J1MRT6LV-2, jvr:-MQRWZGD9-T, jvr:-P2QPF94S-4, jvr:-KGJR5LMZ-R, jvr:-GTZLS67Q-4, jvr:-KC9GD4TJ-Z, jvr:-GB2CPLP0-S ;
  dc:modified "2015-11-23"^^xsd:date ;
  mesh:allowableQualifier jvr:-NFTHND7Q-8, jvr:-NHL3D2X0-S, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-SBNWSM1T-R, jvr:-BT300B3G-Q, jvr:-N2WP45CN-V, jvr:-T9HQD7ST-J, jvr:-TJHVZCRZ-0, jvr:-FWD2BGQ0-9, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-D0F21513-5, jvr:-NKM836P1-M, jvr:-CJXMKG5Q-F, jvr:-NB0XHT3S-N, jvr:-Q3979798-W, jvr:-WK5F724J-1, jvr:-G30ZJ446-J, jvr:-G7KXQWSR-5, jvr:-WZF2ZR3L-B, jvr:-CB30NGKB-3, jvr:-R0ZCQ8X6-J, jvr:-THHNVC7V-3, jvr:-S0CS1X5R-5, jvr:-L6C0XPHT-4, jvr:-HQRFT0C6-B ;
  skos:hiddenLabel "Peptides de signalisation intracellulaire"@fr, "Intracellular Signaling Proteins"@en, "Protéines de signalisation intracellulaire"@fr, "Intracellular Signaling Peptides"@en, "Peptides de signalisation intra-cellulaire"@fr, "Protéines de signalisation intra-cellulaire"@fr ;
  skos:prefLabel "Intracellular Signaling Peptides and Proteins"@en, "Protéines et peptides de signalisation intracellulaire"@fr ;
  dc:established "2005-01-01"^^xsd:date ;
  a skos:Concept, mesh:Descriptor ;
  skos:broader jvr:-FXZ4TQX5-5, jvr:-PC7B4NHS-1 ;
  skos:altLabel "Protéines et peptides de signalisation intra-cellulaire"@fr ;
  skos:inScheme jvr: ;
  dc:created "2004-07-07"^^xsd:date ;
  skos:definition "Proteins and peptides that are involved in SIGNAL TRANSDUCTION within the cell. Included here are peptides and proteins that regulate the activity of TRANSCRIPTION FACTORS and cellular processes in response to signals from CELL SURFACE RECEPTORS. Intracellular signaling peptide and proteins may be part of an enzymatic signaling cascade or act through binding to and modifying the action of other signaling factors."@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D047908> .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-KGJR5LMZ-R
  skos:prefLabel "Axin Signaling Complex"@en, "Complexe de signalisation de l'axine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-MRZHSG15-F
  skos:prefLabel "Mucin-4"@en, "Mucine-4"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-QZQDLP50-T
  skos:prefLabel "Protéine-1 du complexe de la sclérose tubéreuse"@fr, "Tuberous Sclerosis Complex 1 Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-FXZ4TQX5-5
  skos:prefLabel "Proteins"@en, "Protéines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-RZ7ZF59C-G .

jvr:-P7BBLCJT-3
  skos:prefLabel "3',5'-Cyclic-AMP Phosphodiesterases"@fr, "3',5'-Cyclic-AMP Phosphodiesterases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-QPM1CPT8-5
  skos:prefLabel "Phosphoinositide Phospholipase C"@fr, "Phosphoinositide Phospholipase C"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-JCR5Q238-4
  skos:prefLabel "Intracellular Calcium-Sensing Proteins"@en, "Protéines intracellulaires sensibles au calcium"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-GTZLS67Q-4
  skos:prefLabel "Protéine EWS de liaison à l'ARN"@fr, "RNA-Binding Protein EWS"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-MD4CN4SF-H
  skos:prefLabel "Protéine myristoylée riche en alanine et substrat de la kinase C"@fr, "Myristoylated Alanine-Rich C Kinase Substrate"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-W43TNHW6-1
  skos:prefLabel "Cyclines"@fr, "Cyclins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RZ7ZF59C-G .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .