@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-J2WR5R8H-Q
  skos:prefLabel "Colony-Stimulating Factors"@en, "Facteurs de stimulation des colonies"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-RXM7WLB1-5 .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-CZM1BBQL-X
  skos:prefLabel "Récepteur de facteur de croissance granulocytaire"@fr, "Receptors, Granulocyte Colony-Stimulating Factor"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-RXM7WLB1-5 .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RXM7WLB1-5
  skos:altLabel "Facteur stimulant la formation de colonies de neutrophiles"@fr, "Facteur de croissance des granulocytes"@fr, "Facteur de croissance des colonies granulocytaires"@fr, "143011-72-7"@fr, "143011-72-7"@en, "Facteur stimulant les colonies de granulocytes"@fr, "GCSF"@fr, "Facteur stimulant la formation de colonies de granulocytes neutrophiles"@fr, "Colony-stimulating factor, granulocyte"@fr, "Colony-stimulating factor, granulocyte"@en, "Facteur de croissance granulocytaire"@fr, "G-CSF"@fr, "G-CSF"@en ;
  mesh:allowableQualifier jvr:-NFTHND7Q-8, jvr:-T2TS0S41-N, jvr:-R3QWLHRG-V, jvr:-BT300B3G-Q, jvr:-S0CS1X5R-5, jvr:-W6SQV79N-S, jvr:-T9HQD7ST-J, jvr:-Q3979798-W, jvr:-L6C0XPHT-4, jvr:-G7KXQWSR-5, jvr:-HQRFT0C6-B, jvr:-TJHVZCRZ-0, jvr:-NB0XHT3S-N, jvr:-N2WP45CN-V, jvr:-NHL3D2X0-S, jvr:-G30ZJ446-J, jvr:-M63HSDM7-1, jvr:-FWD2BGQ0-9, jvr:-SBNWSM1T-R, jvr:-NKM836P1-M, jvr:-WK5F724J-1, jvr:-XV06LPML-W, jvr:-CB30NGKB-3, jvr:-WZF2ZR3L-B, jvr:-CJXMKG5Q-F, jvr:-THHNVC7V-3, jvr:-D0F21513-5, jvr:-H7K65Q8S-Z, jvr:-Z9TSGBXH-4, jvr:-R0ZCQ8X6-J ;
  skos:related jvr:-CZM1BBQL-X ;
  skos:prefLabel "Facteur de stimulation des colonies de granulocytes"@fr, "Granulocyte Colony-Stimulating Factor"@en ;
  skos:narrower jvr:-Z80VPZXG-J, jvr:-LKX7GLB9-4 ;
  a skos:Concept, mesh:Descriptor ;
  skos:inScheme jvr: ;
  skos:definition "A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines."@en ;
  dc:established "1991-01-01"^^xsd:date ;
  dc:modified "2011-06-24"^^xsd:date ;
  dc:created "1990-06-19"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D016179> ;
  skos:broader jvr:-J2WR5R8H-Q .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LKX7GLB9-4
  skos:prefLabel "Lenograstim"@en, "Lénograstim"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RXM7WLB1-5 .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z80VPZXG-J
  skos:prefLabel "Filgrastim"@fr, "Filgrastim"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-RXM7WLB1-5 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .