@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-K8TXN0VW-X skos:prefLabel "Anticorps"@fr, "Antibodies"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-RVJQJZZG-0 . jvr:-F1N1Z62Z-V skos:prefLabel "Radioimmunotherapy"@en, "Radioimmunothérapie"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-RVJQJZZG-0 . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RBB5D30Q-K skos:prefLabel "Cytotoxicité immunologique"@fr, "Cytotoxicity, Immunologic"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-RVJQJZZG-0 . jvr:-RVJQJZZG-0 a skos:Concept, mesh:Descriptor ; mesh:allowableQualifier jvr:-N2WP45CN-V, jvr:-G30ZJ446-J, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-FWD2BGQ0-9, jvr:-L6C0XPHT-4, jvr:-H7K65Q8S-Z, jvr:-WK5F724J-1, jvr:-G7KXQWSR-5, jvr:-Q3979798-W, jvr:-NHL3D2X0-S, jvr:-CB30NGKB-3, jvr:-T2TS0S41-N, jvr:-BT300B3G-Q, jvr:-TJHVZCRZ-0, jvr:-Z9TSGBXH-4, jvr:-XV06LPML-W, jvr:-SBNWSM1T-R, jvr:-WZF2ZR3L-B, jvr:-NFTHND7Q-8, jvr:-W6SQV79N-S, jvr:-S0CS1X5R-5, jvr:-HQRFT0C6-B, jvr:-NKM836P1-M ; skos:hiddenLabel "Anticorps monoclonal bispécifique"@fr, "Bispecific Monoclonal Antibodies"@en, "Anticorps monoclonaux bi-spécifiques"@fr, "Anticorps monoclonaux bispécifiques"@fr, "Anticorps monoclonal bi-spécifique"@fr ; skos:altLabel "Anticorps bifonctionnel"@fr, "Anticorps bispécifique"@fr, "Anticorps bi-fonctionnels"@fr, "Bifunctional Antibodies"@en, "Anticorps bi-spécifiques"@fr, "Anticorps bi-fonctionnel"@fr, "Bispecific Antibodies"@en, "Anticorps bi-spécifique"@fr, "Anticorps bifonctionnels"@fr ; skos:prefLabel "Antibodies, Bispecific"@en, "Anticorps bispécifiques"@fr ; dc:established "1994-01-01"^^xsd:date ; skos:definition "Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors."@en ; skos:related jvr:-F1N1Z62Z-V, jvr:-ZZSRCDKN-W, jvr:-TKX12FSH-F, jvr:-RBB5D30Q-K ; dc:created "1993-06-04"^^xsd:date ; skos:broader jvr:-K8TXN0VW-X ; mesh:pharmacologicalAction jvr:-RBRTJ68X-8 ; skos:inScheme jvr: ; owl:sameAs ; dc:modified "2010-06-25"^^xsd:date . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-RBRTJ68X-8 skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ; a mesh:Descriptor, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-ZZSRCDKN-W skos:prefLabel "Antibody Specificity"@en, "Spécificité des anticorps"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-RVJQJZZG-0 . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TKX12FSH-F skos:prefLabel "Immunotoxines"@fr, "Immunotoxins"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-RVJQJZZG-0 . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .