@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RSCZK066-5
  mesh:allowableQualifier jvr:-XV06LPML-W, jvr:-Z9TSGBXH-4, jvr:-L6C0XPHT-4, jvr:-W6SQV79N-S, jvr:-CJXMKG5Q-F, jvr:-NFTHND7Q-8, jvr:-Q3979798-W, jvr:-R3QWLHRG-V, jvr:-CB30NGKB-3, jvr:-D0F21513-5, jvr:-NKM836P1-M, jvr:-M63HSDM7-1, jvr:-FWD2BGQ0-9, jvr:-NB0XHT3S-N, jvr:-G30ZJ446-J, jvr:-T9HQD7ST-J, jvr:-SBNWSM1T-R, jvr:-G7KXQWSR-5, jvr:-T2TS0S41-N, jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-R0ZCQ8X6-J, jvr:-N2WP45CN-V, jvr:-WK5F724J-1, jvr:-WZF2ZR3L-B, jvr:-NHL3D2X0-S, jvr:-HQRFT0C6-B, jvr:-THHNVC7V-3, jvr:-S0CS1X5R-5, jvr:-BT300B3G-Q ;
  skos:hiddenLabel "Protéine SIR du type conjugant de Saccharomyces cerevisiae"@fr, "Protéine SIR du type conjugant de S. cerevisiae"@fr, "Silent Mating Type Information Regulator Protein, S cerevisiae"@en, "Protéine SIR mating-type de Saccharomyces cerevisiae"@fr ;
  skos:prefLabel "Protéines SIR de Saccharomyces cerevisiae"@fr, "Silent Information Regulator Proteins, Saccharomyces cerevisiae"@en ;
  a mesh:Descriptor, skos:Concept ;
  dc:established "2003-01-01"^^xsd:date ;
  skos:inScheme jvr: ;
  dc:modified "2005-06-30"^^xsd:date ;
  skos:altLabel "Protéines SIR de S. cerevisiae"@fr, "Silent Information Regulator Proteins, S cerevisiae"@en, "SIR Proteins, S cerevisiae"@en ;
  skos:broader jvr:-HH6T9P1K-W, jvr:-G79VWKTR-5 ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D038281> ;
  skos:related jvr:-ZN52ZLS2-M ;
  skos:definition "A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS."@en ;
  dc:created "2002-07-03"^^xsd:date .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-HH6T9P1K-W
  skos:prefLabel "Nuclear Proteins"@en, "Protéines nucléaires"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-RSCZK066-5 .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZN52ZLS2-M
  skos:prefLabel "Sirtuins"@en, "Sirtuines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-RSCZK066-5 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G79VWKTR-5
  skos:prefLabel "Protéines de Saccharomyces cerevisiae"@fr, "Saccharomyces cerevisiae Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-RSCZK066-5 .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .