@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-J23LGK93-0 mesh:pharmacologicalAction jvr:-R91RZH6C-P .
jvr:-R91RZH6C-P
  mesh:allowableQualifier jvr:-THHNVC7V-3, jvr:-BT300B3G-Q, jvr:-NKM836P1-M, jvr:-H7K65Q8S-Z, jvr:-HQRFT0C6-B, jvr:-T9HQD7ST-J, jvr:-FWD2BGQ0-9, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-NHL3D2X0-S, jvr:-TJHVZCRZ-0, jvr:-G30ZJ446-J, jvr:-Q3979798-W, jvr:-D0F21513-5, jvr:-NB0XHT3S-N, jvr:-SBNWSM1T-R, jvr:-WK5F724J-1, jvr:-W6SQV79N-S, jvr:-XV06LPML-W, jvr:-L6C0XPHT-4, jvr:-R3QWLHRG-V, jvr:-NFTHND7Q-8 ;
  skos:altLabel "Inhibiteurs du cotransporteur sensible au bumétanide"@fr, "Na-K-CL Symporter Inhibitors"@en, "Inhibiteurs du symporteur sodium-potassium-chlore"@fr, "Inhibiteurs du co-transport de sodium-potassium-chlore"@fr, "Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors"@en, "Sodium Potassium Chloride Cotransporter Inhibitors"@en, "Inhibiteurs du symporteur Na-K-Cl"@fr, "Inhibiteurs du cotransport de type symport Na-K-Cl"@fr, "Inhibiteurs du cotransport sodium-potassium-chlore sensible au bumétanide"@fr, "Inhibiteurs du co-transport Na-K-Cl"@fr, "Inhibiteurs du cotransporteur Na-K-Cl"@fr ;
  skos:broader jvr:-RZWRW1JM-Z, jvr:-JQCG9VKP-7 ;
  skos:hiddenLabel "Loop Diuretic"@en, "Loop Diuretics"@en, "Diurétiques à plafond élevé"@fr, "Diurétiques de l'anse de Henle"@fr, "High Ceiling Diuretics"@en, "Diurétiques de l'anse"@fr ;
  skos:inScheme jvr: ;
  dc:established "2006-01-01"^^xsd:date ;
  dc:modified "2020-05-27"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D049994> ;
  a skos:Concept, mesh:Descriptor ;
  skos:definition "Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA."@en ;
  skos:prefLabel "Inhibiteurs du symport chlorure potassium sodium"@fr, "Sodium Potassium Chloride Symporter Inhibitors"@en ;
  dc:created "2005-06-30"^^xsd:date .

jvr:-JQCG9VKP-7
  skos:prefLabel "Modulateurs du transport transmembranaire"@fr, "Membrane Transport Modulators"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-R91RZH6C-P .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RZWRW1JM-Z
  skos:prefLabel "Diurétiques"@fr, "Diuretics"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-R91RZH6C-P .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-J6XVT2VK-C mesh:pharmacologicalAction jvr:-R91RZH6C-P .
jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XXZPG8K2-X mesh:pharmacologicalAction jvr:-R91RZH6C-P .
jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .