@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R2G7RTL4-B
  mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-N2WP45CN-V, jvr:-SBNWSM1T-R, jvr:-BT300B3G-Q, jvr:-L6C0XPHT-4, jvr:-HQRFT0C6-B, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-R0ZCQ8X6-J, jvr:-T2TS0S41-N, jvr:-CJXMKG5Q-F, jvr:-G30ZJ446-J, jvr:-CB30NGKB-3, jvr:-FWD2BGQ0-9, jvr:-THHNVC7V-3, jvr:-M63HSDM7-1, jvr:-Q3979798-W, jvr:-R3QWLHRG-V, jvr:-WK5F724J-1, jvr:-TJHVZCRZ-0, jvr:-NKM836P1-M, jvr:-NFTHND7Q-8, jvr:-XV06LPML-W, jvr:-WZF2ZR3L-B, jvr:-S0CS1X5R-5, jvr:-G7KXQWSR-5, jvr:-H7K65Q8S-Z, jvr:-T9HQD7ST-J ;
  skos:prefLabel "Complement C3 Nephritic Factor"@en, "Facteur néphritique C3"@fr ;
  a mesh:Descriptor, skos:Concept ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D003178> ;
  skos:broader jvr:-G9SZ92LQ-9, jvr:-KTC04NZM-T ;
  skos:altLabel "C3NeF"@fr, "Facteur néphrétique C3"@fr, "Facteur néphrétique C3-NeF"@fr, "Facteur néphritique C3NeF"@fr, "C 3 Nephritic Factor"@en, "Complement 3 Nephritic Factor"@en, "Facteur néphrétique C3NeF"@fr, "C3 Nephritic Factor"@en, "Facteur néphritique C3-NeF"@fr ;
  mesh:pharmacologicalAction jvr:-RBRTJ68X-8, jvr:-VK207D7G-4 ;
  skos:definition "An IgG autoantibody against the ALTERNATIVE PATHWAY C3 CONVERTASE, found in serum of patients with MESANGIOCAPILLARY GLOMERULONEPHRITIS. The binding of this autoantibody to C3bBb stabilizes the enzyme thus reduces the actions of C3b inactivators (COMPLEMENT FACTOR H; COMPLEMENT FACTOR I). This abnormally stabilized enzyme induces a continuous COMPLEMENT ACTIVATION and generation of C3b thereby promoting the assembly of MEMBRANE ATTACK COMPLEX and cytolysis."@en ;
  skos:inScheme jvr: ;
  dc:established "1991-01-01"^^xsd:date ;
  dc:modified "2009-07-30"^^xsd:date ;
  dc:created "1977-05-20"^^xsd:date .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-VK207D7G-4
  skos:prefLabel "Complement Inactivating Agents"@en, "Inhibiteurs du complément"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RBRTJ68X-8
  skos:prefLabel "Facteurs immunologiques"@fr, "Immunologic Factors"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-KTC04NZM-T
  skos:prefLabel "Autoanticorps"@fr, "Autoantibodies"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-R2G7RTL4-B .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G9SZ92LQ-9
  skos:prefLabel "Complement Inactivator Proteins"@en, "Protéines inhibitrices du complément"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-R2G7RTL4-B .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .