@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-KM4BWVZB-P
  skos:prefLabel "Proto-Oncogene Proteins c-crk"@en, "Protéines proto-oncogènes c-crk"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-HM42GS6G-P
  skos:prefLabel "Arrestins"@en, "Arrestines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-W2BMR98B-Q
  skos:prefLabel "Crk-Associated Substrate Protein"@en, "Protéine BCAR1"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-QL35BZGZ-C
  skos:narrower jvr:-J24GD6N6-D, jvr:-B7T6BNLG-P, jvr:-VXV00RKZ-M, jvr:-WKL7DBC8-G, jvr:-XXMMR4Z0-M, jvr:-N7PRLXRT-X, jvr:-W2BMR98B-Q, jvr:-ZLJNQF1K-G, jvr:-X9DT2LR9-R, jvr:-VQQ6WNBR-9, jvr:-N858M3F3-C, jvr:-WFJRNH36-2, jvr:-DHR60FZQ-Q, jvr:-ZXMHMRBX-9, jvr:-VHHW7922-X, jvr:-VV2CZKFX-0, jvr:-HSM2M31L-2, jvr:-KGHHM5B2-1, jvr:-D9WLRMBJ-B, jvr:-MRGDRJVF-Q, jvr:-ZK611792-1, jvr:-MCG7KKW6-T, jvr:-GG7NFKDX-L, jvr:-N3QX0LHC-T, jvr:-PTQZ8WPS-G, jvr:-KDTF8BHB-3, jvr:-F9NT3K04-B, jvr:-KCX05HW8-C, jvr:-J41VMJK0-P, jvr:-QQTMVKPN-6, jvr:-FBTSQFF8-7, jvr:-QX63P50H-3, jvr:-KM4BWVZB-P, jvr:-TL3GQPF5-F, jvr:-HM42GS6G-P, jvr:-LMFXKCX2-0, jvr:-VNNJB7ZF-M, jvr:-ZX4CK2LZ-V, jvr:-R0CL2W05-B, jvr:-Q71GSTG8-K, jvr:-BGRRFPXR-N, jvr:-JZGWCP0H-H, jvr:-HXF6MT47-F, jvr:-PCCM714Q-7, jvr:-SLH6F417-C, jvr:-W9GT174J-0 ;
  skos:prefLabel "Protéines adaptatrices de la transduction du signal"@fr, "Adaptor Proteins, Signal Transducing"@en ;
  mesh:allowableQualifier jvr:-T9HQD7ST-J, jvr:-L6C0XPHT-4, jvr:-NHL3D2X0-S, jvr:-D0F21513-5, jvr:-R0ZCQ8X6-J, jvr:-CJXMKG5Q-F, jvr:-G7KXQWSR-5, jvr:-Q3979798-W, jvr:-S0CS1X5R-5, jvr:-H7K65Q8S-Z, jvr:-XV06LPML-W, jvr:-NB0XHT3S-N, jvr:-W6SQV79N-S, jvr:-HQRFT0C6-B, jvr:-NFTHND7Q-8, jvr:-FWD2BGQ0-9, jvr:-BT300B3G-Q, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-WZF2ZR3L-B, jvr:-Z9TSGBXH-4, jvr:-TJHVZCRZ-0, jvr:-M63HSDM7-1, jvr:-SBNWSM1T-R, jvr:-R3QWLHRG-V, jvr:-G30ZJ446-J, jvr:-N2WP45CN-V, jvr:-THHNVC7V-3, jvr:-WK5F724J-1 ;
  skos:broader jvr:-T3MW8KQR-J, jvr:-RZ7ZF59C-G ;
  skos:inScheme jvr: ;
  dc:modified "2015-11-23"^^xsd:date ;
  dc:established "2005-01-01"^^xsd:date ;
  skos:altLabel "Protéines adaptatrices de la transduction des signaux"@fr, "Signal Transducing Adaptor Proteins"@en ;
  a skos:Concept, mesh:Descriptor ;
  skos:definition "A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes"@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D048868> ;
  dc:created "2004-07-07"^^xsd:date .

jvr:-VV2CZKFX-0
  skos:prefLabel "Facteurs de régulation d'interféron"@fr, "Interferon Regulatory Factors"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-J41VMJK0-P
  skos:prefLabel "Cavéoline-2"@fr, "Caveolin 2"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-GG7NFKDX-L
  skos:prefLabel "Protéines adaptatrices de signalisation NOD"@fr, "Nod Signaling Adaptor Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-HSM2M31L-2
  skos:prefLabel "Homologue-1 de la protéine Discs Large"@fr, "Discs Large Homolog 1 Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-J24GD6N6-D
  skos:prefLabel "Inhibiteurs de STAT activés"@fr, "Protein Inhibitors of Activated STAT"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-VNNJB7ZF-M
  skos:prefLabel "Facteur de différenciation myéloïde-88"@fr, "Myeloid Differentiation Factor 88"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N858M3F3-C
  skos:prefLabel "Kelch-Like ECH-Associated Protein 1"@en, "Protéine-1 de type kelch associée à ECH"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-VHHW7922-X
  skos:prefLabel "Protéine de régulation associée à mTOR"@fr, "Regulatory-Associated Protein of mTOR"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-KCX05HW8-C
  skos:prefLabel "Cavéoline-1"@fr, "Caveolin 1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-T3MW8KQR-J
  skos:prefLabel "Protéines de transport"@fr, "Carrier Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-QL35BZGZ-C .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PTQZ8WPS-G
  skos:prefLabel "Interferon-Stimulated Gene Factor 3"@en, "Complexe ISGF3"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-ZXMHMRBX-9
  skos:prefLabel "Protéines d'activation de la 5-lipoxygénase"@fr, "5-Lipoxygenase-Activating Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DHR60FZQ-Q
  skos:prefLabel "Receptor Activity-Modifying Proteins"@en, "Protéines modifiant l'activité des récepteurs"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-WKL7DBC8-G
  skos:prefLabel "Cortactin"@en, "Cortactine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZK611792-1
  skos:prefLabel "Facteurs de transcription STAT"@fr, "STAT Transcription Factors"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-X9DT2LR9-R
  skos:prefLabel "Protéines et peptides associés aux récepteurs des facteurs de nécrose tumorale"@fr, "Tumor Necrosis Factor Receptor-Associated Peptides and Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-QQTMVKPN-6
  skos:prefLabel "Protéines Smad"@fr, "Smad Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-QX63P50H-3
  skos:prefLabel "Protéines proto-oncogènes c-vav"@fr, "Proto-Oncogene Proteins c-vav"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-VXV00RKZ-M
  skos:prefLabel "GRB10 Adaptor Protein"@en, "Protéine adaptatrice GRB10"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MRGDRJVF-Q
  skos:prefLabel "Paxillin"@en, "Paxilline"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-SLH6F417-C
  skos:prefLabel "Shc Signaling Adaptor Proteins"@en, "Protéines adaptatrices de signalisation Shc"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-JZGWCP0H-H
  skos:prefLabel "Nuclear Receptor Coactivators"@en, "Coactivateurs de récepteurs nucléaires"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-N7PRLXRT-X
  skos:prefLabel "Transcriptional Coactivator with PDZ-Binding Motif Proteins"@en, "Transcriptional coactivator with PDZ-binding motif proteins"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-LMFXKCX2-0
  skos:prefLabel "Complexe médiateur"@fr, "Mediator Complex"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-VQQ6WNBR-9
  skos:prefLabel "Syntenins"@en, "Synténines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WFJRNH36-2
  skos:prefLabel "Protéines SOCS"@fr, "Suppressor of Cytokine Signaling Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-W9GT174J-0
  skos:prefLabel "Protéines Dishevelled"@fr, "Dishevelled Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0CL2W05-B
  skos:prefLabel "mTOR Associated Protein, LST8 Homolog"@en, "Protéine homologue de LST8 associée à MTOR"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-N3QX0LHC-T
  skos:prefLabel "Protéine associée aux molécules de signalisation de l'activation des lymphocytes"@fr, "Signaling Lymphocytic Activation Molecule Associated Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-XXMMR4Z0-M
  skos:prefLabel "Angiomotins"@en, "Angiomotines"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FBTSQFF8-7
  skos:prefLabel "Protéines d'ancrage aux protéines kinases A"@fr, "A Kinase Anchor Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-TL3GQPF5-F
  skos:prefLabel "Protéines d'échafaudage Homer"@fr, "Homer Scaffolding Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-D9WLRMBJ-B
  skos:prefLabel "Protéines adaptatrices de signalisation CARD"@fr, "CARD Signaling Adaptor Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-MCG7KKW6-T
  skos:prefLabel "Sequestosome-1 Protein"@en, "Séquestosome-1"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-KGHHM5B2-1
  skos:prefLabel "Protéines adaptatrices de signalisation des récepteurs à domaine de mort"@fr, "Death Domain Receptor Signaling Adaptor Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PCCM714Q-7
  skos:prefLabel "Substrats du récepteur à l'insuline"@fr, "Insulin Receptor Substrate Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-Q71GSTG8-K
  skos:prefLabel "Protéine-1 interagissant avec le récepteur nucléaire"@fr, "Nuclear Receptor Interacting Protein 1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-RZ7ZF59C-G
  skos:prefLabel "Intracellular Signaling Peptides and Proteins"@en, "Protéines et peptides de signalisation intracellulaire"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-QL35BZGZ-C .

jvr:-ZX4CK2LZ-V
  skos:prefLabel "Protéines de régulation du métabolisme azoté"@fr, "PII Nitrogen Regulatory Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-HXF6MT47-F
  skos:prefLabel "GRB2 Adaptor Protein"@en, "Protéine adaptatrice GRB2"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZLJNQF1K-G
  skos:prefLabel "GRB7 Adaptor Protein"@en, "Protéine adaptatrice GRB7"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-BGRRFPXR-N
  skos:prefLabel "Retinoblastoma Binding Proteins"@en, "Protéines de liaison à la protéine du rétinoblastome"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-B7T6BNLG-P
  skos:prefLabel "Protéines de signalisation YAP"@fr, "YAP-Signaling Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-KDTF8BHB-3
  skos:prefLabel "Protéines 14-3-3"@fr, "14-3-3 Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-F9NT3K04-B
  skos:prefLabel "Compagnon de mTOR insensible à la rapamycine"@fr, "Rapamycin-Insensitive Companion of mTOR Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-QL35BZGZ-C .