@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-WWJHCQRB-K skos:prefLabel "surgery (Qualifier)"@en, "chirurgie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-SDXQ5280-F skos:prefLabel "mortality (Qualifier)"@en, "mortalité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HPKB70N8-W skos:prefLabel "rehabilitation (Qualifier)"@en, "rééducation et réadaptation (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-VG20R78F-K skos:prefLabel "embryologie (Qualificatif)"@fr, "embryology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-QHV8D3Q6-Q mesh:allowableQualifier jvr:-CSKTXWF5-F, jvr:-Z9TSGBXH-4, jvr:-KRXG97RR-5, jvr:-DH7H9MJ2-N, jvr:-T6JZ48ZV-N, jvr:-P31C9JZH-X, jvr:-NHL3D2X0-S, jvr:-W6T67RP3-2, jvr:-S0CS1X5R-5, jvr:-BQ3W1P91-F, jvr:-P1X8SCQ6-K, jvr:-L6C0XPHT-4, jvr:-XV06LPML-W, jvr:-HPKB70N8-W, jvr:-XVHTZRCG-7, jvr:-BBD0S71C-R, jvr:-WWJHCQRB-K, jvr:-W6SQV79N-S, jvr:-SDPG013V-D, jvr:-SBNWSM1T-R, jvr:-WQ00QWRG-J, jvr:-J9Z93VFN-9, jvr:-RC3PND0F-S, jvr:-BT300B3G-Q, jvr:-T1QJHLQ4-J, jvr:-CB30NGKB-3, jvr:-MDQBX560-1, jvr:-KFM33PF8-L, jvr:-GXVR9QN8-P, jvr:-VG20R78F-K, jvr:-JVKFK2NX-2, jvr:-W4X1LN61-R, jvr:-SDXQ5280-F, jvr:-ZJBZVRWR-8, jvr:-B6C87218-T ; dc:created "1991-05-30"^^xsd:date ; skos:altLabel "Insuffisance ovarienne prématurée"@fr, "Défaillance ovarienne précoce"@fr, "IOP (Insuffisance Ovarienne Primitive)"@fr, "Insuffisance ovarienne précoce"@fr, "Premature Ovarian Failure"@en, "Défaillance ovarienne prématurée"@fr, "Ovarian Failure, Premature"@en, "IOP (Insuffisance Ovarienne Prématurée)"@fr, "Insuffisance ovarienne primaire"@fr ; skos:hiddenLabel "Syndrome des ovaires résistants"@fr, "Resistant Ovary Syndrome"@en, "Syndrome de l'ovaire résistant aux gonadotrophines"@fr, "Syndrome de résistance ovarienne aux gonadotrophines"@fr, "Premature Ovarian Failure 1"@en, "Fragile X Premature Ovarian Failure"@en, "Primary Ovarian Insufficiency, Fragile X-Associated"@en, "Syndrome des ovaires résistant aux gonadotrophines"@fr, "Gonadotropin-Resistant Ovary Syndrome"@en, "Syndrome de résistance ovarienne"@fr, "X-Linked Hypergonadotropic Ovarian Failure"@en, "Syndrome des ovaires résistant aux gonadotropines"@fr, "Fragile X-Associated Primary Ovarian Insufficiency"@en, "Premature Ovarian Failure, X-Linked"@en, "Syndrome des ovaires résistants aux gonadotropines"@fr, "Hypergonadotropic Ovarian Failure, X-Linked"@en, "FMR1-Related Primary Ovarian Insufficiency"@en ; dc:established "1992-01-01"^^xsd:date ; a skos:Concept, mesh:Descriptor ; skos:related jvr:-J955MV62-L ; skos:prefLabel "Primary Ovarian Insufficiency"@en, "Insuffisance ovarienne primitive"@fr ; owl:sameAs ; skos:definition "Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene. A form of ovarian failure, caused by resistance to GONADOTROPINS stimulation. It may be caused by defects in the receptors for FOLLICLE STIMULATING HORMONE or LUTEINIZING HORMONE. It may be due to factors interfering with the actions of gonadotropins, such as antibodies blocking the ligand-receptor interaction."@en ; skos:inScheme jvr: ; dc:modified "2021-06-30"^^xsd:date ; skos:broader jvr:-ZFHK40R6-7 . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-J955MV62-L skos:prefLabel "Menopause, Premature"@en, "Ménopause précoce"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-QHV8D3Q6-Q . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-WQ00QWRG-J skos:prefLabel "physiopathologie (Qualificatif)"@fr, "physiopathology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-DH7H9MJ2-N skos:prefLabel "anatomopathologie (Qualificatif)"@fr, "pathology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-MDQBX560-1 skos:prefLabel "radiotherapy (Qualifier)"@en, "radiothérapie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZJBZVRWR-8 skos:prefLabel "parasitologie (Qualificatif)"@fr, "parasitology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-W6T67RP3-2 skos:prefLabel "diagnostic imaging (Qualifier)"@en, "imagerie diagnostique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-B6C87218-T skos:prefLabel "prévention et contrôle (Qualificatif)"@fr, "prevention & control (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-BQ3W1P91-F skos:prefLabel "thérapie (Qualificatif)"@fr, "therapy (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KRXG97RR-5 skos:prefLabel "diagnostic (Qualificatif)"@fr, "diagnosis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-J9Z93VFN-9 skos:prefLabel "enzymology (Qualifier)"@en, "enzymologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T1QJHLQ4-J skos:prefLabel "microbiology (Qualifier)"@en, "microbiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-P31C9JZH-X skos:prefLabel "congénital (Qualificatif)"@fr, "congenital (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-KFM33PF8-L skos:prefLabel "médecine vétérinaire (Qualificatif)"@fr, "veterinary (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-BBD0S71C-R skos:prefLabel "induit chimiquement (Qualificatif)"@fr, "chemically induced (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XVHTZRCG-7 skos:prefLabel "étiologie (Qualificatif)"@fr, "etiology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-P1X8SCQ6-K skos:prefLabel "virologie (Qualificatif)"@fr, "virology (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T6JZ48ZV-N skos:prefLabel "complications (Qualifier)"@en, "complications (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-SDPG013V-D skos:prefLabel "psychology (Qualifier)"@en, "psychologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-GXVR9QN8-P skos:prefLabel "drug therapy (Qualifier)"@en, "traitement médicamenteux (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZFHK40R6-7 skos:prefLabel "Ovarian Diseases"@en, "Maladies ovariennes"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-QHV8D3Q6-Q . jvr:-CSKTXWF5-F skos:prefLabel "epidemiology (Qualifier)"@en, "épidémiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-JVKFK2NX-2 skos:prefLabel "nursing (Qualifier)"@en, "soins infirmiers (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W4X1LN61-R skos:prefLabel "diet therapy (Qualifier)"@en, "diétothérapie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-RC3PND0F-S skos:prefLabel "ethnology (Qualifier)"@en, "ethnologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .