@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-Q348J1QC-B
  mesh:allowableQualifier jvr:-T9HQD7ST-J, jvr:-FWD2BGQ0-9, jvr:-NHL3D2X0-S, jvr:-G7KXQWSR-5, jvr:-L6C0XPHT-4, jvr:-WZF2ZR3L-B, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-S0CS1X5R-5, jvr:-THHNVC7V-3, jvr:-CB30NGKB-3, jvr:-W6SQV79N-S, jvr:-BT300B3G-Q, jvr:-WK5F724J-1, jvr:-R3QWLHRG-V, jvr:-SBNWSM1T-R, jvr:-CJXMKG5Q-F, jvr:-G30ZJ446-J, jvr:-HQRFT0C6-B, jvr:-NFTHND7Q-8, jvr:-N2WP45CN-V, jvr:-TJHVZCRZ-0, jvr:-Q3979798-W, jvr:-XV06LPML-W, jvr:-T2TS0S41-N, jvr:-M63HSDM7-1, jvr:-NKM836P1-M, jvr:-NB0XHT3S-N ;
  skos:hiddenLabel "EC 2.3.2.27"@fr, "EC 2.3.2.27"@en, "EC 2.3.2.26"@fr, "EC 2.3.2.26"@en ;
  skos:narrower jvr:-T977GPNW-G, jvr:-WNTTPC8V-K, jvr:-Q8FV865Z-G, jvr:-Q5F0LWJ9-W, jvr:-BG00SJ00-G, jvr:-MM6PJP1T-2, jvr:-PS7JLQPW-M, jvr:-N1SGHV88-P, jvr:-MR615SKC-F, jvr:-DPKQXD31-G, jvr:-X6MWLJSP-7, jvr:-ZP60TN2N-X, jvr:-TGHHZ6XH-T ;
  skos:altLabel "Ubiquitine-protéine ligase"@fr, "Ubiquitin-Protein Ligase"@en, "E3 Ubiquitin Ligase"@en, "Ligase E3 ubiquitine-protéine"@fr, "Ubiquitin Ligase E3"@en, "Ligase E3 de l'ubiquitine"@fr, "Ligases ubiquitine-protéine"@fr, "Ligase E3"@fr, "Ligase ubiquitine-protéine"@fr, "Ubiquitin-Protein Ligase E3"@en, "E3 Ligase"@en ;
  mesh:registryNumber "EC 2.3.2.26", "EC 2.3.2.27" ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D044767> ;
  skos:prefLabel "Ubiquitin-protein ligases"@fr, "Ubiquitin-Protein Ligases"@en ;
  dc:modified "2016-06-02"^^xsd:date ;
  skos:definition "A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes."@en ;
  a skos:Concept, mesh:Descriptor ;
  dc:established "2004-01-01"^^xsd:date ;
  skos:inScheme jvr: ;
  skos:broader jvr:-K58LPDJM-S ;
  dc:created "2003-07-09"^^xsd:date .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-DPKQXD31-G
  skos:prefLabel "Protéine Von Hippel-Lindau supresseur de tumeur"@fr, "Von Hippel-Lindau Tumor Suppressor Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-Q8FV865Z-G
  skos:prefLabel "Protéine-3 induite par le facteur de nécrose tumorale alpha"@fr, "Tumor Necrosis Factor alpha-Induced Protein 3"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-N1SGHV88-P
  skos:prefLabel "Proto-Oncogene Proteins c-cbl"@en, "Protéines proto-oncogènes c-cbl"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BG00SJ00-G
  skos:prefLabel "Proto-Oncogene Proteins c-mdm2"@en, "Protéines proto-oncogènes c-mdm2"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-MM6PJP1T-2
  skos:prefLabel "Protéine du groupe de complémentation L de l'anémie de Fanconi"@fr, "Fanconi Anemia Complementation Group L Protein"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-K58LPDJM-S
  skos:prefLabel "Ubiquitin-protein ligase complexes"@fr, "Ubiquitin-Protein Ligase Complexes"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-Q348J1QC-B .

jvr:-Q5F0LWJ9-W
  skos:prefLabel "Inhibitor of Apoptosis Proteins"@en, "Protéines IAP"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MR615SKC-F
  skos:prefLabel "Ubiquitine protéine ligases NEDD4"@fr, "Nedd4 Ubiquitin Protein Ligases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-X6MWLJSP-7
  skos:prefLabel "Receptors, Autocrine Motility Factor"@en, "Récepteur du facteur autocrine de motilité"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZP60TN2N-X
  skos:prefLabel "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein"@en, "Protéine-1 de translocation de lymphome du tissu lymphoïde associé aux muqueuses"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-PS7JLQPW-M
  skos:prefLabel "Polycomb Repressive Complex 1"@en, "Complexe répresseur Polycomb-1"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-TGHHZ6XH-T
  skos:prefLabel "Tripartite Motif-Containing Protein 28"@en, "Protéine-28 à motif tripartite"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T977GPNW-G
  skos:prefLabel "SKP Cullin F-Box Protein Ligases"@en, "SKP cullin F-box protein ligases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-WNTTPC8V-K
  skos:prefLabel "Anaphase-Promoting Complex-Cyclosome"@en, "Complexe promoteur de l'anaphase"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-Q348J1QC-B .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .