@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJ580XM9-W skos:prefLabel "Anti-HIV Agents"@en, "Agents antiVIH"@fr ; a mesh:Descriptor, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-WJFDLBW4-7 skos:prefLabel "Antimetabolites"@en, "Antimétabolites"@fr ; a mesh:Descriptor, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZLHNZQS7-1 skos:prefLabel "Didéoxynucléosides"@fr, "Dideoxynucleosides"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-PLNR7NBH-G . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G4R176S9-J skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HKVQ0KFW-S skos:prefLabel "Inhibiteurs de la transcriptase inverse"@fr, "Reverse Transcriptase Inhibitors"@en ; a mesh:Descriptor, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-PLNR7NBH-G mesh:allowableQualifier jvr:-R0ZCQ8X6-J, jvr:-Q3979798-W, jvr:-H7K65Q8S-Z, jvr:-G4R176S9-J, jvr:-NHL3D2X0-S, jvr:-S0CS1X5R-5, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-D0F21513-5, jvr:-NFTHND7Q-8, jvr:-M63HSDM7-1, jvr:-L6C0XPHT-4, jvr:-T9HQD7ST-J, jvr:-R3QWLHRG-V, jvr:-G30ZJ446-J, jvr:-NB0XHT3S-N, jvr:-WK5F724J-1, jvr:-BT300B3G-Q, jvr:-THHNVC7V-3, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-XV06LPML-W, jvr:-FWD2BGQ0-9 ; a skos:Concept, mesh:Descriptor ; skos:broader jvr:-ZLHNZQS7-1, jvr:-BKP2X0RB-J ; skos:altLabel "3'-Azido-2',3'-Dideoxythymidine"@en, "AZT, Antiviral"@en, "Azidothymidine"@fr, "Azidothymidine"@en, "3'-Azido-3'-deoxythymidine"@en, "AZT Antiviral"@en, "4B9XT59T7S"@fr, "4B9XT59T7S"@en, "AZT (Azidothymidine)"@fr, "Thymidine, 3'-azido-3'-deoxy-"@fr, "Thymidine, 3'-azido-3'-deoxy-"@en, "3'-Azido-3'-désoxythymidine"@fr, "30516-87-1 (Zidovudine)"@fr, "30516-87-1 (Zidovudine)"@en, "AZT (Antiviral)"@en, "3'-Azido-3'-désoxy-thymidine"@fr ; dc:modified "2016-06-01"^^xsd:date ; dc:established "1989-01-01"^^xsd:date ; skos:hiddenLabel "BWA-509U"@fr, "BWA-509U"@en, "BW A509U"@fr, "BW A509U"@en, "Retrovir"@en, "BWA509U"@fr ; owl:sameAs ; skos:definition "A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia."@en ; mesh:pharmacologicalAction jvr:-HKVQ0KFW-S, jvr:-WJFDLBW4-7, jvr:-TJ580XM9-W ; dc:created "1988-05-09"^^xsd:date ; skos:inScheme jvr: ; skos:prefLabel "Zidovudine"@en, "Zidovudine"@fr . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-BKP2X0RB-J skos:prefLabel "Thymidine"@en, "Thymidine"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-PLNR7NBH-G . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .