@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix owl: . @prefix dc: . @prefix xsd: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-ZF2HCQ6X-4 skos:prefLabel "Syndrome de Rothmund-Thomson"@fr, "Rothmund-Thomson Syndrome"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-PKBG384J-0 . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-DM26165D-D skos:prefLabel "Syndrome de Bloom"@fr, "Bloom Syndrome"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-PKBG384J-0 . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-XXK7J0FK-N skos:prefLabel "Syndrome de Werner"@fr, "Werner Syndrome"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-PKBG384J-0 . jvr:-R6PH0S8T-L skos:prefLabel "Helicase"@fr, "DNA Helicases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-PKBG384J-0 . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HHKM343N-2 skos:prefLabel "Werner syndrome helicase"@fr, "Werner Syndrome Helicase"@en ; a mesh:Descriptor, skos:Concept ; skos:broader jvr:-PKBG384J-0 . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-PKBG384J-0 skos:altLabel "Protéine RecQ"@fr, "RecQ Family of DNA Helicase"@en, "RecQ family of DNA helicases"@fr, "RecQ Family of DNA Helicases"@en, "Hélicases RecQ"@fr, "RecQ Helicase"@en, "RecQ Protein"@en ; mesh:allowableQualifier jvr:-W6SQV79N-S, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-D0F21513-5, jvr:-Z9TSGBXH-4, jvr:-H7K65Q8S-Z, jvr:-THHNVC7V-3, jvr:-WZF2ZR3L-B, jvr:-M63HSDM7-1, jvr:-XV06LPML-W, jvr:-FWD2BGQ0-9, jvr:-NKM836P1-M, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-Q3979798-W, jvr:-WK5F724J-1, jvr:-G7KXQWSR-5, jvr:-R3QWLHRG-V, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-T9HQD7ST-J, jvr:-T2TS0S41-N, jvr:-NB0XHT3S-N, jvr:-CJXMKG5Q-F, jvr:-NHL3D2X0-S, jvr:-N2WP45CN-V, jvr:-CB30NGKB-3, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8 ; skos:hiddenLabel "RecQL Helicase"@fr, "RecQL Helicase"@en, "RecQ2 Helicase"@en, "RecQ2 Helicase"@fr, "DNA Helicase RecQL"@fr, "DNA Helicase RecQL"@en, "ATP-Dependent DNA Helicase Q5"@fr, "ATP-Dependent DNA Helicase Q5"@en, "Hélicase RecQ3"@fr, "Hélicase RecQL3"@fr, "EC 3.6.4.12"@fr, "EC 3.6.4.12"@en, "Hélicase RecQL"@fr, "RecQL4 Helicase"@fr, "RecQL4 Helicase"@en, "Hélicase RecQL1"@fr, "Hélicase RecQL5"@fr, "Hélicase RecQ4"@fr, "DNA Helicase RecQL4"@en, "DNA Helicase RecQL4"@fr, "RTS Helicase"@en, "RTS Helicase"@fr, "RecQ4 Helicase"@en, "RecQ4 Helicase"@fr, "DNA Helicase, RecQ-like type 2"@fr, "DNA Helicase, RecQ-like type 2"@en, "RecQL2 Helicase"@fr, "RecQ5 Helicase"@en, "RecQ5 Helicase"@fr, "RecQL2 Helicase"@en, "RecQ5L Helicase"@en, "RecQ5L Helicase"@fr, "RecQ3 Helicase"@en, "RecQ3 Helicase"@fr, "DNA Helicase Q1"@en, "DNA Helicase Q1"@fr, "RecQL3 Helicase"@en, "RecQL3 Helicase"@fr, "Hélicase RecQ5"@fr, "ATP-Dependent DNA Helicase Q1"@en, "ATP-Dependent DNA Helicase Q1"@fr, "RECQL1 Helicase"@fr, "RECQL1 Helicase"@en, "Hélicase RecQ2"@fr, "ATP-Dependent DNA Helicase Q4"@en, "ATP-Dependent DNA Helicase Q4"@fr, "Hélicase RecQL2"@fr, "DNA-Dependent ATPase Q1"@en, "Hélicase RecQL4"@fr ; skos:inScheme jvr: ; a mesh:Descriptor, skos:Concept ; skos:prefLabel "RecQ helicases"@fr, "RecQ Helicases"@en ; skos:related jvr:-XXK7J0FK-N, jvr:-DM26165D-D, jvr:-ZF2HCQ6X-4 ; skos:narrower jvr:-HHKM343N-2 ; owl:sameAs ; skos:definition "A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging."@en ; dc:created "2006-07-05"^^xsd:date ; dc:established "2007-01-01"^^xsd:date ; dc:modified "2020-05-27"^^xsd:date ; skos:broader jvr:-R6PH0S8T-L ; mesh:registryNumber "EC 3.6.4.12" . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .