@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-SJ04HSDQ-C mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-NLBR2DQD-0 mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-GZMVXVQG-H
  skos:prefLabel "Antagonistes du récepteur de type 1 de l'angiotensine-II"@fr, "Angiotensin II Type 1 Receptor Blockers"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-PCSM8M59-2 .

jvr:-D5BZWFDV-F mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FGPTNL02-8 mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-ZNQ93WRF-F mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-WVMVLCW7-C
  skos:prefLabel "Vasopeptidase Inhibitors"@en, "Inhibiteurs des vasopeptidases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-PCSM8M59-2 .

jvr:-W4RSPTN2-C
  skos:prefLabel "Protease Inhibitors"@en, "Inhibiteurs de protéases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-PCSM8M59-2 .

jvr:-HWSDV2CJ-V mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-PCSM8M59-2
  skos:narrower jvr:-WVMVLCW7-C ;
  skos:altLabel "ACE Inhibitor"@en, "Inhibiteurs de la kininase II"@fr, "Inhibiteurs de l'enzyme de conversion"@fr, "ACE Inhibitors"@en, "Antagonists, Kininase II"@en, "Angiotensin-Converting Enzyme Inhibitor"@en, "Kininase II Inhibitors"@en, "Inhibiteurs ECA"@fr, "Angiotensin I-Converting Enzyme Inhibitors"@en, "Angiotensin Converting Enzyme Inhibitor"@en, "Inhibiteurs de l'angiotensin converting enzyme"@fr, "Inhibitors, Angiotensin-Converting Enzyme"@en, "Kininase II Antagonists"@en, "Inhibitors, ACE"@en, "IEC (Inhibiteurs de l'Enzyme de Conversion)"@fr, "Angiotensin-Converting Enzyme Antagonists"@en, "Antagonists, Angiotensin-Converting Enzyme"@en, "Inhibitors, Kininase II"@en, "Angiotensin I-Converting Enzyme Inhibitor"@en, "Inhibiteurs ACE"@fr, "Kininase II Inhibitor"@en ;
  mesh:allowableQualifier jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-W6SQV79N-S, jvr:-R3QWLHRG-V, jvr:-TJHVZCRZ-0, jvr:-FWD2BGQ0-9, jvr:-BT300B3G-Q, jvr:-H7K65Q8S-Z, jvr:-XV06LPML-W, jvr:-NB0XHT3S-N, jvr:-S0CS1X5R-5, jvr:-HQRFT0C6-B, jvr:-NFTHND7Q-8, jvr:-T9HQD7ST-J, jvr:-D0F21513-5, jvr:-G30ZJ446-J, jvr:-L6C0XPHT-4, jvr:-CB30NGKB-3, jvr:-THHNVC7V-3, jvr:-NKM836P1-M, jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R ;
  skos:prefLabel "Inhibiteurs de l'enzyme de conversion de l'angiotensine"@fr, "Angiotensin-Converting Enzyme Inhibitors"@en ;
  dc:created "1987-05-04"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-W4RSPTN2-C ;
  skos:related jvr:-FG8LP9J8-Q, jvr:-GZMVXVQG-H, jvr:-WRZGM6MM-2 ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000806> ;
  skos:inScheme jvr: ;
  dc:modified "2020-05-27"^^xsd:date ;
  dc:established "1988-01-01"^^xsd:date ;
  skos:definition "A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility."@en .

jvr:-FG8LP9J8-Q
  skos:prefLabel "Antihypertensive Agents"@en, "Antihypertenseurs"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-PCSM8M59-2 .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-XF81R66V-3 mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-P9LNTDXZ-L mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WRZGM6MM-2
  skos:prefLabel "Système rénine-angiotensine"@fr, "Renin-Angiotensin System"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-PCSM8M59-2 .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-DJ7R0Z9T-S mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NR94SJDS-1 mesh:pharmacologicalAction jvr:-PCSM8M59-2 .
jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .