@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-S2FN6N83-K
  skos:prefLabel "Mutagens"@en, "Mutagènes"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-PCGD0J2R-7 .

jvr:-DSH0SDBB-W mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-FH87846H-P mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-K1KBCK17-0 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-LRRS3LHV-5 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-JBVL80X3-V mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z4W97DZK-0 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-N4RQNGXF-9 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-FLJ1DHK1-L mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-HKNH4N78-2
  skos:prefLabel "Mécanismes moléculaires de l'action pharmacologique"@fr, "Molecular Mechanisms of Pharmacological Action"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-PCGD0J2R-7 .

jvr: a skos:ConceptScheme .
jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-B3DB4FH6-F mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-KBLWNJWG-6 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RH7RGR6D-2
  skos:prefLabel "Antineoplastic Agents, Alkylating"@en, "Antinéoplasiques alcoylants"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-PCGD0J2R-7 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-C294ML8T-7 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M7M2L15Z-C mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RG47XCHJ-N mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WB9B1FKG-8 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-S1JFLTH9-3
  skos:prefLabel "Noxas"@fr, "Noxae"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-PCGD0J2R-7 .

jvr:-K9P55PSB-7 mesh:pharmacologicalAction jvr:-PCGD0J2R-7 .
jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PCGD0J2R-7
  mesh:allowableQualifier jvr:-TJHVZCRZ-0, jvr:-H7K65Q8S-Z, jvr:-W6SQV79N-S, jvr:-NFTHND7Q-8, jvr:-L6C0XPHT-4, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-D0F21513-5, jvr:-CB30NGKB-3, jvr:-THHNVC7V-3, jvr:-S0CS1X5R-5, jvr:-BT300B3G-Q, jvr:-T9HQD7ST-J, jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R, jvr:-R3QWLHRG-V, jvr:-XV06LPML-W, jvr:-HQRFT0C6-B, jvr:-NKM836P1-M, jvr:-NB0XHT3S-N ;
  a skos:Concept, mesh:Descriptor ;
  skos:inScheme jvr: ;
  skos:altLabel "Agents alkylants"@fr, "Alkylants"@fr, "Alkylators"@en, "Alkylator"@en, "Alcoylants"@fr, "Alkylating Agent"@en, "Agents alkoylants"@fr ;
  dc:established "1966-01-01"^^xsd:date ;
  skos:broader jvr:-HKNH4N78-2, jvr:-S1JFLTH9-3 ;
  skos:narrower jvr:-RH7RGR6D-2 ;
  skos:related jvr:-S2FN6N83-K ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000477> ;
  skos:prefLabel "Alkylating Agents"@en, "Agents alcoylants"@fr ;
  dc:created "1999-01-01"^^xsd:date ;
  skos:definition "Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases."@en ;
  dc:modified "2020-05-27"^^xsd:date .