@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7P55V6J-D
  skos:prefLabel "Isoindoles"@fr, "Isoindoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-P5KMK826-R .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-DPB2JZPS-T
  skos:prefLabel "Antagonistes des récepteurs 5-HT2 de la sérotonine"@fr, "Serotonin 5-HT2 Receptor Antagonists"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BPCJCPK8-3
  skos:prefLabel "Thiazoles"@fr, "Thiazoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-P5KMK826-R .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-P5KMK826-R
  mesh:allowableQualifier jvr:-XV06LPML-W, jvr:-FWD2BGQ0-9, jvr:-T9HQD7ST-J, jvr:-Q3979798-W, jvr:-R0ZCQ8X6-J, jvr:-TJHVZCRZ-0, jvr:-W6SQV79N-S, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-CB30NGKB-3, jvr:-NFTHND7Q-8, jvr:-S0CS1X5R-5, jvr:-NHL3D2X0-S, jvr:-L6C0XPHT-4, jvr:-G30ZJ446-J, jvr:-M63HSDM7-1, jvr:-HQRFT0C6-B, jvr:-THHNVC7V-3, jvr:-R3QWLHRG-V, jvr:-BT300B3G-Q, jvr:-G4R176S9-J, jvr:-H7K65Q8S-Z, jvr:-SBNWSM1T-R, jvr:-WK5F724J-1, jvr:-NKM836P1-M ;
  skos:altLabel "367514-88-3 (lurasidone hydrochloride)"@fr, "367514-88-3 (lurasidone hydrochloride)"@en, "22IC88528T"@fr, "22IC88528T"@en, "Lurasidone HCl"@en, "367514-87-2 (lurasidone)"@fr, "367514-87-2 (lurasidone)"@en, "O0P4I5851I"@fr, "O0P4I5851I"@en ;
  dc:created "2015-07-09"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-FRV1PNZN-9, jvr:-DPB2JZPS-T, jvr:-PRPPKQT3-0, jvr:-P9M1898G-2 ;
  skos:definition "A thiazole derivative and atypical ANTIPSYCHOTIC AGENT that functions as a DOPAMINE D2 RECEPTOR ANTAGONIST; SEROTONIN 5-HT2 RECEPTOR ANTAGONIST, serotonin 5-HT7 receptor antagonist, and antagonist of the adrenergic α2A and α2C receptors, as well as a partial SEROTONIN 5-HT1A RECEPTOR AGONIST. It is used in the treatment of SCHIZOPHRENIA and BIPOLAR DISORDER."@en ;
  skos:broader jvr:-BPCJCPK8-3, jvr:-G7P55V6J-D ;
  skos:hiddenLabel "SM-13496"@fr, "SM-13496"@en, "SM 13496"@en, "SM13496"@fr, "SM13496"@en, "N-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinylmethyl)-1-cyclohexylmethyl)-2,3-bicyclo(2.2.1)heptanedicarboximide"@en, "Lurasidone"@fr, "Lurasidone"@en, "Latuda"@en, "SM-13,496"@en ;
  a skos:Concept, mesh:Descriptor ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000069056> ;
  dc:modified "2016-05-31"^^xsd:date ;
  dc:established "2016-01-01"^^xsd:date ;
  skos:prefLabel "Chlorhydrate de lurasidone"@fr, "Lurasidone Hydrochloride"@en ;
  skos:inScheme jvr: .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-P9M1898G-2
  skos:prefLabel "Antagonistes des récepteurs alpha-2 adrénergiques"@fr, "Adrenergic alpha-2 Receptor Antagonists"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PRPPKQT3-0
  skos:prefLabel "Antagonistes du récepteur D2 de la dopamine"@fr, "Dopamine D2 Receptor Antagonists"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FRV1PNZN-9
  skos:prefLabel "Antipsychotic Agents"@en, "Neuroleptiques"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .