@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-BXVMNJSN-S
  skos:prefLabel "Apoptose"@fr, "Apoptosis"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-P073TW3D-8 .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z8JL6BJ0-7
  skos:prefLabel "Cysteine Endopeptidases"@en, "Cysteine endopeptidases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-P073TW3D-8 .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W7JTHW7W-1
  skos:prefLabel "Caspases, Effector"@en, "Caspases effectrices"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-P073TW3D-8 .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-ZP60TN2N-X
  skos:prefLabel "Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein"@en, "Protéine-1 de translocation de lymphome du tissu lymphoïde associé aux muqueuses"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-P073TW3D-8 .

jvr:-B8KSSJCV-G
  skos:prefLabel "Caspases initiatrices"@fr, "Caspases, Initiator"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-P073TW3D-8 .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-P073TW3D-8
  mesh:allowableQualifier jvr:-Q3979798-W, jvr:-BT300B3G-Q, jvr:-H7K65Q8S-Z, jvr:-D0F21513-5, jvr:-N2WP45CN-V, jvr:-WZF2ZR3L-B, jvr:-NFTHND7Q-8, jvr:-L6C0XPHT-4, jvr:-WK5F724J-1, jvr:-R3QWLHRG-V, jvr:-CB30NGKB-3, jvr:-NB0XHT3S-N, jvr:-THHNVC7V-3, jvr:-HQRFT0C6-B, jvr:-W6SQV79N-S, jvr:-XV06LPML-W, jvr:-NHL3D2X0-S, jvr:-SBNWSM1T-R, jvr:-T2TS0S41-N, jvr:-NKM836P1-M, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-CJXMKG5Q-F, jvr:-G7KXQWSR-5, jvr:-Z9TSGBXH-4, jvr:-TJHVZCRZ-0, jvr:-T9HQD7ST-J, jvr:-S0CS1X5R-5 ;
  skos:definition "A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur."@en ;
  skos:altLabel "Caspase"@en ;
  skos:broader jvr:-Z8JL6BJ0-7, jvr:-G373PN6Q-J ;
  mesh:registryNumber "EC 3.4.22.-" ;
  a skos:Concept, mesh:Descriptor ;
  skos:narrower jvr:-B8KSSJCV-G, jvr:-W7JTHW7W-1, jvr:-ZP60TN2N-X ;
  dc:created "1998-06-10"^^xsd:date ;
  dc:established "1999-01-01"^^xsd:date ;
  dc:modified "2021-05-21"^^xsd:date ;
  skos:inScheme jvr: ;
  skos:related jvr:-BXVMNJSN-S ;
  skos:hiddenLabel "EC 3.4.22.-"@en, "EC 3.4.22.-"@fr ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D020169> ;
  skos:prefLabel "Caspases"@en, "Caspases"@fr .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G373PN6Q-J
  skos:prefLabel "Protéines régulatrices de l'apoptose"@fr, "Apoptosis Regulatory Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-P073TW3D-8 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .