@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-V94HRFZQ-X
  skos:prefLabel "Serine Proteases"@en, "Protéases à sérine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-NZCLV6XQ-1 .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NZCLV6XQ-1
  mesh:allowableQualifier jvr:-XV06LPML-W, jvr:-R3QWLHRG-V, jvr:-S0CS1X5R-5, jvr:-WK5F724J-1, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-SBNWSM1T-R, jvr:-CB30NGKB-3, jvr:-NHL3D2X0-S, jvr:-Z9TSGBXH-4, jvr:-THHNVC7V-3, jvr:-H7K65Q8S-Z, jvr:-TJHVZCRZ-0, jvr:-W6SQV79N-S, jvr:-T2TS0S41-N, jvr:-BT300B3G-Q, jvr:-WZF2ZR3L-B, jvr:-L6C0XPHT-4, jvr:-NKM836P1-M, jvr:-T9HQD7ST-J, jvr:-NB0XHT3S-N, jvr:-G7KXQWSR-5, jvr:-M63HSDM7-1, jvr:-Q3979798-W, jvr:-D0F21513-5, jvr:-NFTHND7Q-8, jvr:-CJXMKG5Q-F, jvr:-HQRFT0C6-B, jvr:-N2WP45CN-V ;
  skos:altLabel "Protéine CLN2"@fr, "CLN2 Protein"@en, "Tripeptidyl Protease I"@en, "Tripeptidyl Peptidase I"@en, "Tripeptidyl-peptidase I"@fr, "TPP1 Protein"@en, "Tripeptidyl aminopeptidase I"@fr, "Tripeptidyl protease I"@fr, "Tripeptidyl Aminopeptidase I"@en, "Tripeptidyl-Peptidase I"@en, "Protéine TPP1"@fr ;
  skos:inScheme jvr: ;
  dc:modified "2022-04-29"^^xsd:date ;
  skos:prefLabel "Tripeptidyl-Peptidase 1"@en, "Tripeptidyl-peptidase-1"@fr ;
  skos:hiddenLabel "EC 3.4.14.9"@fr, "EC 3.4.14.9"@en ;
  a skos:Concept, mesh:Descriptor ;
  dc:created "2021-07-09"^^xsd:date ;
  skos:broader jvr:-LKT56TMR-G, jvr:-V94HRFZQ-X, jvr:-QC4WM9VR-M ;
  dc:established "2022-01-01"^^xsd:date ;
  skos:definition "Lysosomal Serine proteases that release N-terminal tripeptide from a polypeptide and cleave peptides between hydrophobic residues. An enzyme that in humans encoded by the TPP1 gene. It is involved in the degradation of bone collagen. Mutations in this gene are associated with the CEROID LIPOFUSCINOSIS, NEURONAL, 2; and SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE CEROID LIPOFUSCINOSIS, NEURONAL, 2; AND SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 7."@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000091346> ;
  mesh:registryNumber "EC 3.4.14.9" .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LKT56TMR-G
  skos:prefLabel "Aminopeptidases"@fr, "Aminopeptidases"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-NZCLV6XQ-1 .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-QC4WM9VR-M
  skos:prefLabel "Dipeptidyl-Peptidases and Tripeptidyl-Peptidases"@en, "Dipeptidyl-Peptidases and Tripeptidyl-Peptidases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-NZCLV6XQ-1 .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .