@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-SLLN8F4V-8
  skos:prefLabel "Anticonvulsants"@en, "Anticonvulsivants"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-NH16BPHN-8
  skos:hiddenLabel "Valproate de calcium"@fr, "Valproate de magnésium"@fr, "Depakote"@en, "Dipropyl-acétate"@fr, "Dipropyl Acetate"@en, "Valproate"@fr, "Depakene"@en, "Valproate"@en, "Valproate de sodium"@fr, "Divalproex Sodium"@en, "Propylisopropylacetic Acid"@en, "Sodium Valproate"@en, "Valproate sodique"@fr, "Valproate Sodium"@en, "Valproate Calcium"@en, "Ergenyl"@en, "Vupral"@en, "Magnesium Valproate"@en, "Depakine"@en, "Valproic Acid, Sodium Salt (2:1)"@en, "Convulsofin"@en, "Calcium Valproate"@en, "Semisodium Valproate"@en, "Dipropylacétate"@fr ;
  mesh:pharmacologicalAction jvr:-RNN9WKG8-L, jvr:-N1VNQB90-R, jvr:-CL96NQQZ-V, jvr:-SLLN8F4V-8 ;
  skos:prefLabel "Acide valproïque"@fr, "Valproic Acid"@en ;
  mesh:allowableQualifier jvr:-G4R176S9-J, jvr:-H7K65Q8S-Z, jvr:-WK5F724J-1, jvr:-XV06LPML-W, jvr:-CB30NGKB-3, jvr:-G30ZJ446-J, jvr:-R3QWLHRG-V, jvr:-D0F21513-5, jvr:-S0CS1X5R-5, jvr:-NFTHND7Q-8, jvr:-NKM836P1-M, jvr:-HQRFT0C6-B, jvr:-NB0XHT3S-N, jvr:-L6C0XPHT-4, jvr:-BT300B3G-Q, jvr:-THHNVC7V-3, jvr:-Q3979798-W, jvr:-TJHVZCRZ-0, jvr:-R0ZCQ8X6-J, jvr:-W6SQV79N-S, jvr:-T9HQD7ST-J, jvr:-NHL3D2X0-S, jvr:-FWD2BGQ0-9, jvr:-SBNWSM1T-R, jvr:-M63HSDM7-1 ;
  dc:modified "2018-06-19"^^xsd:date ;
  skos:altLabel "2-Propylpentanoic Acid"@en, "Divalproex"@en, "56CCK4F86G"@fr, "56CCK4F86G"@en, "644VL95AO6"@fr, "644VL95AO6"@en, "99-66-1 (Valproic Acid)"@fr, "99-66-1 (Valproic Acid)"@en, "Q400352CM2"@fr, "Q400352CM2"@en, "614OI1Z5WI"@fr, "614OI1Z5WI"@en, "76584-70-8 (Na salt (2:1))"@fr, "76584-70-8 (Na salt (2:1))"@en, "Acide 2-propylpentanoïque"@fr, "Pentanoic acid, 2-propyl-"@fr, "Pentanoic acid, 2-propyl-"@en, "5VOM6GYJ0D"@fr, "5VOM6GYJ0D"@en, "Acide 2-propyl-pentanoïque"@fr ;
  dc:established "1979-01-01"^^xsd:date ;
  a mesh:Descriptor, skos:Concept ;
  skos:definition "A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS."@en ;
  skos:inScheme jvr: ;
  skos:broader jvr:-RMSDR6RG-5 ;
  dc:created "1974-11-11"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D014635> .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N1VNQB90-R
  skos:prefLabel "Antimaniacodépressifs"@fr, "Antimanic Agents"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CL96NQQZ-V
  skos:prefLabel "GABA Agents"@en, "Agents GABA"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RNN9WKG8-L
  skos:prefLabel "Enzyme Inhibitors"@en, "Antienzymes"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-RMSDR6RG-5
  skos:prefLabel "Pentanoic Acids"@en, "Acides pentanoïques"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-NH16BPHN-8 .