@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-KR314PF5-R
  skos:prefLabel "Ibandronic Acid"@en, "Acide ibandronique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-CH7B8P55-F
  skos:prefLabel "Clodronic Acid"@en, "Acide clodronique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CZFXD7TR-P
  skos:prefLabel "Risedronic Acid"@en, "Acide risédronique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-VLHKC09M-T
  skos:prefLabel "Etidronic Acid"@en, "Acide étidronique"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NBRNK6HL-M
  dc:established "1977-01-01"^^xsd:date ;
  mesh:allowableQualifier jvr:-WK5F724J-1, jvr:-CB30NGKB-3, jvr:-D0F21513-5, jvr:-L6C0XPHT-4, jvr:-HQRFT0C6-B, jvr:-THHNVC7V-3, jvr:-W6SQV79N-S, jvr:-NB0XHT3S-N, jvr:-R0ZCQ8X6-J, jvr:-G30ZJ446-J, jvr:-FWD2BGQ0-9, jvr:-T9HQD7ST-J, jvr:-NHL3D2X0-S, jvr:-S0CS1X5R-5, jvr:-R3QWLHRG-V, jvr:-Q3979798-W, jvr:-XV06LPML-W, jvr:-M63HSDM7-1, jvr:-H7K65Q8S-Z, jvr:-NKM836P1-M, jvr:-TJHVZCRZ-0, jvr:-SBNWSM1T-R, jvr:-NFTHND7Q-8, jvr:-BT300B3G-Q ;
  skos:broader jvr:-J1QNM3Z0-0 ;
  skos:narrower jvr:-GPNDRJM9-B, jvr:-CD3LRKVK-P, jvr:-VLHKC09M-T, jvr:-CZFXD7TR-P, jvr:-CH7B8P55-F, jvr:-HDBRW0MF-R, jvr:-VP1L0TTZ-B, jvr:-KR314PF5-R ;
  dc:created "1976-04-16"^^xsd:date ;
  skos:inScheme jvr: ;
  skos:altLabel "Bisphosphonates"@en, "Bisphosphonate"@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D004164> ;
  skos:definition "Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents."@en ;
  dc:modified "2020-05-27"^^xsd:date ;
  mesh:pharmacologicalAction jvr:-BBJDHV4W-1 ;
  a skos:Concept, mesh:Descriptor ;
  skos:prefLabel "Diphosphonates"@en, "Diphosphonates"@fr .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-GPNDRJM9-B
  skos:prefLabel "Acide zolédronique"@fr, "Zoledronic Acid"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-VP1L0TTZ-B
  skos:prefLabel "Pamidronate"@en, "Pamidronate"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-CD3LRKVK-P
  skos:prefLabel "Alendronate"@fr, "Alendronate"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-J1QNM3Z0-0
  skos:prefLabel "Phosphonates"@fr, "Organophosphonates"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-NBRNK6HL-M .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-HDBRW0MF-R
  skos:prefLabel "Médronate de technétium (99mTc)"@fr, "Technetium Tc 99m Medronate"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-NBRNK6HL-M .

jvr:-BBJDHV4W-1
  skos:prefLabel "Bone Density Conservation Agents"@en, "Agents de maintien de la densité osseuse"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .