@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LDDSZL0G-Z
  skos:prefLabel "Proto-Oncogene Proteins c-bcr"@en, "Protéines proto-oncogènes c-bcr"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-N7W9SJZJ-8 .

jvr:-QX63P50H-3
  skos:prefLabel "Protéines proto-oncogènes c-vav"@fr, "Proto-Oncogene Proteins c-vav"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-N7W9SJZJ-8 .

jvr:-N7W9SJZJ-8
  mesh:allowableQualifier jvr:-TJHVZCRZ-0, jvr:-Q3979798-W, jvr:-Z9TSGBXH-4, jvr:-M63HSDM7-1, jvr:-WZF2ZR3L-B, jvr:-W6SQV79N-S, jvr:-NFTHND7Q-8, jvr:-R0ZCQ8X6-J, jvr:-T2TS0S41-N, jvr:-N2WP45CN-V, jvr:-CB30NGKB-3, jvr:-THHNVC7V-3, jvr:-G7KXQWSR-5, jvr:-CJXMKG5Q-F, jvr:-NHL3D2X0-S, jvr:-D0F21513-5, jvr:-NB0XHT3S-N, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-XV06LPML-W, jvr:-R3QWLHRG-V, jvr:-H7K65Q8S-Z, jvr:-T9HQD7ST-J, jvr:-HQRFT0C6-B, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-NKM836P1-M, jvr:-S0CS1X5R-5, jvr:-L6C0XPHT-4, jvr:-BT300B3G-Q ;
  skos:hiddenLabel "Rho Guanine Nucleotide Exchange Factor 6"@en, "Facteur-6 d'échange de nucléotide guanylique sur Rho"@fr, "Facteur-1 d'échange de nucléotide guanylique sur Rho"@fr, "p115 RhoGEF"@fr, "p115 RhoGEF"@en, "Rho guanine nucleotide exchange factor 6"@fr, "Rho Guanine Nucleotide Exchange Factor p115"@en, "Facteur-7 d'échange de nucléotide guanylique sur Rho"@fr, "PAK-Interacting Exchange Factor beta"@en, "Protéine Cool-1"@fr, "Cool-1 Protein"@en, "Rho Guanine Nucleotide Exchange Factor (GEF) 1"@en, "Facteur p115 d'échange de nucléotide guanylique sur Rho"@fr, "RhoGEF"@fr, "RhoGEF"@en, "betaPIX Protein"@en, "ARHGEF1"@fr, "ARHGEF1"@en, "beta PIX Protein"@en, "Rho Guanine Nucleotide Exchange Factor 7"@en, "Protéine bêta PIX"@fr, "Rho guanine nucleotide exchange factor p115"@fr, "Rho guanine nucleotide exchange factor 7"@fr, "p115RhoGEF"@en, "p115RhoGEF"@fr, "Protéine bêtaPIX"@fr ;
  skos:narrower jvr:-QX63P50H-3, jvr:-LDDSZL0G-Z ;
  skos:altLabel "Facteurs d'échange de nucléotide guanylique sur Rho"@fr ;
  skos:inScheme jvr: ;
  a mesh:Descriptor, skos:Concept ;
  dc:modified "2015-11-24"^^xsd:date ;
  dc:created "2013-07-08"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D064067> ;
  dc:established "2014-01-01"^^xsd:date ;
  skos:definition "Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways."@en ;
  skos:prefLabel "Rho Guanine Nucleotide Exchange Factors"@en, "Rho guanine nucleotide exchange factors"@fr ;
  skos:broader jvr:-J25NT22T-J .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-J25NT22T-J
  skos:prefLabel "Facteurs d'échange de nucléotides guanyliques"@fr, "Guanine Nucleotide Exchange Factors"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-N7W9SJZJ-8 .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .