@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G7KXQWSR-5
  skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z9TSGBXH-4
  skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T7604J8V-K
  skos:prefLabel "Protéines proto-oncogènes"@fr, "Proto-Oncogene Proteins"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-MTXXNHND-1 .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TP5B7P0H-F
  skos:prefLabel "Protein Serine-Threonine Kinases"@en, "Protein-Serine-Threonine Kinases"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-MTXXNHND-1 .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T2TS0S41-N
  skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CJXMKG5Q-F
  skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-MTXXNHND-1
  skos:broader jvr:-T7604J8V-K, jvr:-TP5B7P0H-F ;
  skos:hiddenLabel "Protein Kinase B gamma"@en, "Protéine kinase AKT1"@fr, "EC 2.7.11.1"@fr, "EC 2.7.11.1"@en, "Protéine Akt-alpha"@fr, "Akt-gamma Protein"@en, "Rac-PK beta Protein"@en, "Proto-Oncogene Proteins c-akt3"@en, "Protéine kinase AKT3"@fr, "Protein Kinase B beta"@en, "Protéines proto-oncogènes c-akt3"@fr, "Akt-beta Protein"@en, "Protéines proto-oncogènes c-akt1"@fr, "Protéine Rac-PK bêta"@fr, "AKT2 Protein Kinase"@en, "Protéine kinase B gamma"@fr, "Akt-alpha Protein"@en, "Proto-Oncogene Proteins c-akt2"@en, "AKT1 Protein Kinase"@en, "Protéine Rac-PK alpha"@fr, "Protein Kinase B alpha"@en, "Protéines proto-oncogènes c-akt2"@fr, "Protéine Akt-bêta"@fr, "Rac-PK alpha Protein"@en, "Protéine kinase AKT2"@fr, "AKT3 Protein Kinase"@en, "Protéine Akt-gamma"@fr, "Protéine kinase B alpha"@fr, "Protéine kinase B bêta"@fr, "Proto-Oncogene Proteins c-akt1"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:altLabel "Proto-Oncogene Protein Akt"@en, "Related to A and C-Protein"@en, "Proto-Oncogene Protein RAC"@en, "Protéine du proto-oncogène akt"@fr, "Protéine proto-oncogène Akt"@fr, "RAC-PK Protein"@en, "c-akt Proto-Oncogene Protein"@en, "Protéine kinase Rac"@fr, "Protéine sérine-thréonine kinase (Rac)"@fr, "Protein-Serine-Threonine Kinase (Rac)"@en, "Protéine du proto-oncogène c-akt"@fr, "Protein Kinase B"@en, "c-akt Protein"@en, "akt Proto-Oncogene Protein"@en, "Rac Protein Kinase"@en, "Related to A and C-protein"@fr, "Protéine RAC-PK"@fr, "RAC (Related to A and C-protein)"@fr, "Protéine c-akt"@fr, "Protéine kinase B"@fr, "Protéine proto-oncogène RAC"@fr ;
  mesh:allowableQualifier jvr:-G7KXQWSR-5, jvr:-WZF2ZR3L-B, jvr:-NB0XHT3S-N, jvr:-Z9TSGBXH-4, jvr:-N2WP45CN-V, jvr:-T9HQD7ST-J, jvr:-TJHVZCRZ-0, jvr:-HQRFT0C6-B, jvr:-M63HSDM7-1, jvr:-W6SQV79N-S, jvr:-CB30NGKB-3, jvr:-XV06LPML-W, jvr:-NHL3D2X0-S, jvr:-NFTHND7Q-8, jvr:-Q3979798-W, jvr:-BT300B3G-Q, jvr:-R3QWLHRG-V, jvr:-NKM836P1-M, jvr:-THHNVC7V-3, jvr:-CJXMKG5Q-F, jvr:-R0ZCQ8X6-J, jvr:-G30ZJ446-J, jvr:-H7K65Q8S-Z, jvr:-FWD2BGQ0-9, jvr:-SBNWSM1T-R, jvr:-L6C0XPHT-4, jvr:-S0CS1X5R-5, jvr:-D0F21513-5, jvr:-T2TS0S41-N, jvr:-WK5F724J-1 ;
  dc:created "2005-06-30"^^xsd:date ;
  dc:established "2006-01-01"^^xsd:date ;
  dc:modified "2021-05-21"^^xsd:date ;
  skos:prefLabel "Protéines proto-oncogènes c-akt"@fr, "Proto-Oncogene Proteins c-akt"@en ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D051057> ;
  mesh:registryNumber "EC 2.7.11.1" ;
  skos:inScheme jvr: ;
  skos:definition "Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells."@en .

jvr:-N2WP45CN-V
  skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WZF2ZR3L-B
  skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .