@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-GHZ9X04M-7
  skos:prefLabel "Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination"@en, "Association de phosphate de sitagliptine et de chlorhydrate de metformine"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-MGHS2S7F-H .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-X0LB1RM3-2
  skos:prefLabel "Incretins"@en, "Incrétines"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-PWZCXDF8-3
  skos:prefLabel "Triazoles"@fr, "Triazoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-MGHS2S7F-H .

jvr:-PXK478FD-S
  skos:prefLabel "Hypoglycemic Agents"@en, "Hypoglycémiants"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CH518C99-1
  skos:prefLabel "Pyrazines"@fr, "Pyrazines"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-MGHS2S7F-H .

jvr:-P4D51Q77-W
  skos:prefLabel "Linagliptine"@fr, "Linagliptin"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-MGHS2S7F-H .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MGHS2S7F-H
  dc:established "2016-01-01"^^xsd:date ;
  mesh:allowableQualifier jvr:-WK5F724J-1, jvr:-Q3979798-W, jvr:-HQRFT0C6-B, jvr:-R0ZCQ8X6-J, jvr:-H7K65Q8S-Z, jvr:-M63HSDM7-1, jvr:-NB0XHT3S-N, jvr:-D0F21513-5, jvr:-W6SQV79N-S, jvr:-L6C0XPHT-4, jvr:-NFTHND7Q-8, jvr:-TJHVZCRZ-0, jvr:-S0CS1X5R-5, jvr:-SBNWSM1T-R, jvr:-THHNVC7V-3, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-BT300B3G-Q, jvr:-XV06LPML-W, jvr:-FWD2BGQ0-9, jvr:-R3QWLHRG-V, jvr:-T9HQD7ST-J, jvr:-G4R176S9-J, jvr:-G30ZJ446-J, jvr:-NHL3D2X0-S ;
  skos:broader jvr:-PWZCXDF8-3, jvr:-CH518C99-1 ;
  mesh:pharmacologicalAction jvr:-NH96NWS6-9, jvr:-X0LB1RM3-2, jvr:-PXK478FD-S ;
  skos:definition "A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES."@en ;
  skos:hiddenLabel "Phosphate de sitagliptine anhydre"@fr, "4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine"@en, "Sitagliptin Phosphate Anhydrous"@en, "Sitagliptin"@en, "MK 0431"@en, "MK0431"@fr, "MK0431"@en, "MK-0431"@fr, "MK-0431"@en, "Januvia"@en, "Sitagliptine"@fr ;
  skos:altLabel "Phosphate de sitagliptine monohydraté"@fr, "QFP0P1DV7Z"@en, "QFP0P1DV7Z"@fr, "TS63EW8X6F"@en, "TS63EW8X6F"@fr, "486460-32-6 (sitagliptin)"@fr, "486460-32-6 (sitagliptin)"@en, "Sitagliptin Phosphate Monohydrate"@en, "654671-77-9 (sitagliptin phosphate)"@fr, "654671-77-9 (sitagliptin phosphate)"@en, "494P4635I6"@fr, "494P4635I6"@en, "Sitagliptin Monophosphate Monohydrate"@en ;
  skos:related jvr:-P4D51Q77-W ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-GHZ9X04M-7 ;
  dc:created "2015-07-09"^^xsd:date ;
  skos:prefLabel "Sitagliptin Phosphate"@en, "Phosphate de sitagliptine"@fr ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000068900> ;
  skos:inScheme jvr: ;
  dc:modified "2016-05-31"^^xsd:date .

jvr:-NH96NWS6-9
  skos:prefLabel "Inhibiteurs de la dipeptidyl-peptidase IV"@fr, "Dipeptidyl-Peptidase IV Inhibitors"@en ;
  a mesh:Descriptor, skos:Concept .