@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-X6NNB38B-S
  skos:prefLabel "Anti-Inflammatory Agents, Non-Steroidal"@en, "Anti-inflammatoires non stéroïdiens"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-MKVNQ0D6-3
  skos:prefLabel "Antirhumatismaux"@fr, "Antirheumatic Agents"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-ZTRBDB9P-Z
  skos:prefLabel "Gastrointestinal Agents"@en, "Agents gastro-intestinaux"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M4QJ5RJ3-6
  skos:broader jvr:-W48M2QVD-H, jvr:-PTWKTRHQ-G ;
  mesh:pharmacologicalAction jvr:-MKVNQ0D6-3, jvr:-ZTRBDB9P-Z, jvr:-H8LJ47P7-S, jvr:-X6NNB38B-S ;
  skos:hiddenLabel "TNF Receptor Type II-IgG Fusion Protein"@en, "Protéine dimérique recombinante humaine de fusion du récepteur du TNF de type II et de l'IgG"@fr, "Protéine de fusion du récepteur du TNF de type II et de l'IgG"@fr, "Etanercept-szzs"@en, "TNTR-Fc"@en, "Recombinant Human Dimeric TNF Receptor Type II-IgG Fusion Protein"@en, "TNT Receptor Fusion Protein"@en, "Protéine de fusion TNFR-Fc"@fr, "TNR 001"@fr, "TNR 001"@en, "TNR-001"@fr, "TNR-001"@en, "Enbrel"@fr, "Enbrel"@en, "Erelzi"@en, "TNFR-Fc Fusion Protein"@en ;
  mesh:allowableQualifier jvr:-G30ZJ446-J, jvr:-FWD2BGQ0-9, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-NKM836P1-M, jvr:-H7K65Q8S-Z, jvr:-BT300B3G-Q, jvr:-HQRFT0C6-B, jvr:-G4R176S9-J, jvr:-L6C0XPHT-4, jvr:-CB30NGKB-3, jvr:-R3QWLHRG-V, jvr:-THHNVC7V-3, jvr:-NHL3D2X0-S, jvr:-TJHVZCRZ-0, jvr:-NFTHND7Q-8, jvr:-XV06LPML-W, jvr:-S0CS1X5R-5, jvr:-T9HQD7ST-J, jvr:-D0F21513-5, jvr:-W6SQV79N-S, jvr:-NB0XHT3S-N ;
  skos:prefLabel "Etanercept"@en, "Étanercept"@fr ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000068800> ;
  skos:altLabel "OP401G7OJC"@fr, "OP401G7OJC"@en, "185243-69-0"@en, "185243-69-0"@fr ;
  dc:established "2016-01-01"^^xsd:date ;
  dc:created "2015-07-09"^^xsd:date ;
  a skos:Concept, mesh:Descriptor ;
  skos:inScheme jvr: ;
  skos:definition "A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS."@en ;
  dc:modified "2017-12-14"^^xsd:date .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-PTWKTRHQ-G
  skos:prefLabel "Receptors, Tumor Necrosis Factor"@en, "Récepteurs aux facteurs de nécrose tumorale"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-M4QJ5RJ3-6 .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H8LJ47P7-S
  skos:prefLabel "Immunosuppresseurs"@fr, "Immunosuppressive Agents"@en ;
  a mesh:Descriptor, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-W48M2QVD-H
  skos:prefLabel "Fragments Fc des immunoglobulines"@fr, "Immunoglobulin Fc Fragments"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-M4QJ5RJ3-6 .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .