@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-BT300B3G-Q skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-XV06LPML-W skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-M1CSSN71-W skos:broader jvr:-Q5F0LWJ9-W ; dc:modified "2017-06-29"^^xsd:date ; mesh:allowableQualifier jvr:-Q3979798-W, jvr:-THHNVC7V-3, jvr:-G30ZJ446-J, jvr:-NFTHND7Q-8, jvr:-FWD2BGQ0-9, jvr:-T9HQD7ST-J, jvr:-WK5F724J-1, jvr:-HQRFT0C6-B, jvr:-H7K65Q8S-Z, jvr:-CB30NGKB-3, jvr:-D0F21513-5, jvr:-G7KXQWSR-5, jvr:-R0ZCQ8X6-J, jvr:-NHL3D2X0-S, jvr:-CJXMKG5Q-F, jvr:-NB0XHT3S-N, jvr:-BT300B3G-Q, jvr:-R3QWLHRG-V, jvr:-L6C0XPHT-4, jvr:-NKM836P1-M, jvr:-M63HSDM7-1, jvr:-XV06LPML-W, jvr:-SBNWSM1T-R, jvr:-Z9TSGBXH-4, jvr:-S0CS1X5R-5, jvr:-W6SQV79N-S, jvr:-N2WP45CN-V, jvr:-WZF2ZR3L-B, jvr:-TJHVZCRZ-0, jvr:-T2TS0S41-N ; mesh:registryNumber "EC 2.3.2.27" ; skos:hiddenLabel "EC 2.3.2.27"@fr, "EC 2.3.2.27"@en ; skos:altLabel "Protéine c-IAP2"@fr, "Cellular Inhibitor of Apoptosis-2"@en, "Protéine BIRC3"@fr, "Baculoviral IAP Repeat Containing Protein 3"@en, "c-IAP2 Protein"@en, "Protéine IAP1"@fr, "IAP1 Protein"@en, "Inhibiteur-2 de l'apoptose"@fr, "Inhibitor of Apoptosis Protein 1"@en, "Protéine cIAP2"@fr, "BIRC3 Protein"@en, "Inhibitor of Apoptosis 1 Protein"@en, "Protéine Hiap-1"@fr, "Hiap-1 Protein"@en, "Apoptosis Inhibitor 2"@en, "Protéine-1 inhibitrice de l'apoptose"@fr, "Inhibiteur cellulaire-2 de l'apoptose"@fr, "cIAP2 Protein"@en ; owl:sameAs ; dc:established "2018-01-01"^^xsd:date ; skos:definition "A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells."@en ; mesh:pharmacologicalAction jvr:-PNZGN6ZW-9 ; a skos:Concept, mesh:Descriptor ; skos:prefLabel "Baculoviral IAP Repeat-Containing 3 Protein"@en, "Protéine-3 contenant des répétitions IAP baculovirales"@fr ; skos:inScheme jvr: ; dc:created "2017-07-11"^^xsd:date . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-G30ZJ446-J skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NFTHND7Q-8 skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-THHNVC7V-3 skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-PNZGN6ZW-9 skos:prefLabel "Inhibiteurs des caspases"@fr, "Caspase Inhibitors"@en ; a mesh:Descriptor, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NB0XHT3S-N skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CB30NGKB-3 skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-R3QWLHRG-V skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-T9HQD7ST-J skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-Q5F0LWJ9-W skos:prefLabel "Inhibitor of Apoptosis Proteins"@en, "Protéines IAP"@fr ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-M1CSSN71-W . jvr:-NKM836P1-M skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WK5F724J-1 skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .