@prefix jvr: . @prefix skos: . @prefix mesh: . @prefix dc: . @prefix xsd: . @prefix owl: . jvr:-PL1B9DKD-D skos:prefLabel "Antley-Bixler Syndrome Phenotype"@en, "Phénotype du syndrome d'Antley-Bixler"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-LSQB2HFM-5 . jvr:-R8DZXWX2-H skos:prefLabel "Récepteurs à activité tyrosine kinase"@fr, "Receptor Protein-Tyrosine Kinases"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-LSQB2HFM-5 . jvr:-L6C0XPHT-4 skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-HNV0R7S6-V skos:prefLabel "Récepteur facteur croissance fibroblaste"@fr, "Receptors, Fibroblast Growth Factor"@en ; a mesh:Descriptor, skos:Concept ; skos:narrower jvr:-LSQB2HFM-5 . jvr:-SJKZ2L64-T skos:prefLabel "Acrocéphalosyndactylie"@fr, "Acrocephalosyndactylia"@en ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-LSQB2HFM-5 . jvr:-LSQB2HFM-5 skos:altLabel "Fibroblast Growth Factor Receptor 2"@en, "Protéine FGFR2"@fr, "Bek Fgf Receptor Kinase"@en, "Bek-Related Fibroblast Growth Factor-Receptor-1"@en, "Fibroblast Growth Factor Receptors 2"@en, "BEK Fibroblast Growth Factor Receptor"@en, "Récepteur 2 du facteur de croissance fibroblastique"@fr, "FGFR2 Protein"@en, "BEK Protein Tyrosine Kinase"@en, "Bek Fgf Receptor kinase"@fr, "BEK Protein tyrosine kinase"@fr, "Récepteur 2 du facteur fibroblastique de croissance"@fr, "BEK Fibroblast Growth Factor Receptor Kinase"@en, "CD332 Antigen"@en ; mesh:allowableQualifier jvr:-FWD2BGQ0-9, jvr:-NHL3D2X0-S, jvr:-N2WP45CN-V, jvr:-HQRFT0C6-B, jvr:-Z9TSGBXH-4, jvr:-WZF2ZR3L-B, jvr:-R0ZCQ8X6-J, jvr:-SBNWSM1T-R, jvr:-TJHVZCRZ-0, jvr:-D0F21513-5, jvr:-L6C0XPHT-4, jvr:-Q3979798-W, jvr:-W6SQV79N-S, jvr:-M63HSDM7-1, jvr:-S0CS1X5R-5, jvr:-T2TS0S41-N, jvr:-H7K65Q8S-Z, jvr:-CJXMKG5Q-F, jvr:-G7KXQWSR-5 ; skos:related jvr:-SJKZ2L64-T, jvr:-F9108BDF-Q, jvr:-PL1B9DKD-D ; skos:hiddenLabel "Fibroblast Growth Factor Receptor 2b"@en, "Fibroblast Growth Factor Receptors 2b"@en, "Récepteur FGFR2b"@fr, "Fibroblast Growth Factor Receptor 2c"@en, "FGFR2b"@fr, "FGFR2b"@en, "Receptor, Fibroblast Growth Factor 2c"@en, "EC 2.7.10.1"@fr, "EC 2.7.10.1"@en, "Récepteur FGFR2c"@fr, "FGFR2c"@en, "FGFR2c"@fr, "Receptor, Fibroblast Growth Factor 2b"@en ; dc:established "2006-01-01"^^xsd:date ; skos:prefLabel "Récepteur FGFR2"@fr, "Receptor, Fibroblast Growth Factor, Type 2"@en ; skos:broader jvr:-R8DZXWX2-H, jvr:-HNV0R7S6-V ; owl:sameAs ; dc:created "2005-06-30"^^xsd:date ; mesh:registryNumber "EC 2.7.10.1" ; skos:definition "A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME). An isoform of fibroblast growth factor receptor 2 found mainly in EPITHELIAL CELLS that is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10."@en ; a skos:Concept, mesh:Descriptor ; dc:modified "2021-05-21"^^xsd:date ; skos:inScheme jvr: . jvr:-G7KXQWSR-5 skos:prefLabel "biosynthèse (Qualificatif)"@fr, "biosynthesis (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-F9108BDF-Q skos:prefLabel "Craniofacial Dysostosis"@en, "Dysostose craniofaciale"@fr ; a mesh:Descriptor, skos:Concept ; skos:related jvr:-LSQB2HFM-5 . jvr:-Z9TSGBXH-4 skos:prefLabel "génétique (Qualificatif)"@fr, "genetics (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-Q3979798-W skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-H7K65Q8S-Z skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-TJHVZCRZ-0 skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-FWD2BGQ0-9 skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-R0ZCQ8X6-J skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-S0CS1X5R-5 skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-M63HSDM7-1 skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-T2TS0S41-N skos:prefLabel "ultrastructure (Qualifier)"@en, "ultrastructure (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-HQRFT0C6-B skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-W6SQV79N-S skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr: a skos:ConceptScheme . jvr:-SBNWSM1T-R skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-CJXMKG5Q-F skos:prefLabel "deficiency (Qualifier)"@en, "déficit (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-D0F21513-5 skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-NHL3D2X0-S skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ; a mesh:Qualifier, skos:Concept . jvr:-N2WP45CN-V skos:prefLabel "drug effects (Qualifier)"@en, "effets des médicaments et des substances chimiques (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept . jvr:-WZF2ZR3L-B skos:prefLabel "physiology (Qualifier)"@en, "physiologie (Qualificatif)"@fr ; a mesh:Qualifier, skos:Concept .