@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-PLJV5R12-5 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-TNK0VHT3-T mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-LJ643ZKX-J mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-RPV00BZH-J mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-X165Z266-H
  skos:prefLabel "Adrenergic beta-Antagonists"@en, "Antagonistes bêta-adrénergiques"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-RT3QLV95-9 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-PFB8MJLD-D mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-DH8ZBHPD-T mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-KJL2M32F-D mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-XSRSX03K-X mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-BTD6F6SH-Z mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-QLBPLFVW-L mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-XFKG6PC1-D mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-ZGR444T5-C mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-KDZD7M9K-G mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-T49SMM98-D mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-PKX4QRPQ-6 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-SV9Z0G51-J mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-SBZ9GPM9-X mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HG8TV9VZ-H mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-BGP0KZ3M-R mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-KK47152P-8 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-Z9C8W29N-2 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-PN3V38RC-6 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-GVDJ9CKK-Q mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-Z6XH0M72-4 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-L95MH335-C mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-W8MNH2H7-8
  skos:prefLabel "Inhibiteurs des canaux calciques"@fr, "Calcium Channel Blockers"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-QZJQZPPM-6 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-ZQS2168K-V
  skos:prefLabel "Inhibiteurs des canaux potassiques"@fr, "Potassium Channel Blockers"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-ZMDMZ0WT-R mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-TC4H7320-6
  skos:prefLabel "Sodium Channel Blockers"@en, "Bloqueurs de canaux sodiques"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-NVGW04D9-D
  skos:prefLabel "Troubles du rythme cardiaque"@fr, "Arrhythmias, Cardiac"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-F265LGNK-T mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-V113QM27-7 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-C93Q9CML-4 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-FC4CKQ03-2 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LGMF688M-P mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-X54LTQMW-8 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Z1FCPT68-T mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-QZBNR627-P mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-GTJV37K0-2 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-LXTK5TPC-W mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-FHJ2K05D-H mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-VFJZQJXM-N mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-NJJSQRRZ-W mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-C1ZWPH34-6 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-F7MHMS1G-Q mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FQ8R4W70-G mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-G7KBTZ7G-9 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-BFM7DX77-4 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-D56R0XCB-7 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-SHWN3GCD-7 mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-LS0SSBHQ-R
  skos:related jvr:-W8MNH2H7-8, jvr:-ZQS2168K-V, jvr:-TC4H7320-6, jvr:-LK745FB8-V, jvr:-X165Z266-H, jvr:-NVGW04D9-D ;
  mesh:allowableQualifier jvr:-L6C0XPHT-4, jvr:-XV06LPML-W, jvr:-W6SQV79N-S, jvr:-HQRFT0C6-B, jvr:-D0F21513-5, jvr:-NKM836P1-M, jvr:-CB30NGKB-3, jvr:-SBNWSM1T-R, jvr:-T9HQD7ST-J, jvr:-S0CS1X5R-5, jvr:-THHNVC7V-3, jvr:-BT300B3G-Q, jvr:-NHL3D2X0-S, jvr:-TJHVZCRZ-0, jvr:-NB0XHT3S-N, jvr:-NFTHND7Q-8, jvr:-WK5F724J-1, jvr:-FWD2BGQ0-9, jvr:-G30ZJ446-J, jvr:-R3QWLHRG-V, jvr:-Q3979798-W, jvr:-H7K65Q8S-Z ;
  skos:prefLabel "Anti-Arrhythmia Agents"@en, "Antiarythmiques"@fr ;
  skos:altLabel "Anti-Arrhythmics"@en, "Antiarrhythmia Agent"@en, "Antiarrhythmia Drugs"@en, "Antiarrhythmic Drugs"@en, "Anti-Arrhythmia Drug"@en, "Antiarrhythmic Drug"@en, "Antiarrhythmia Agents"@en, "Anti-arythmiques"@fr, "Médicaments antiarythmiques"@fr, "Antiarrhythmia Drug"@en, "Anti-Arrhythmia Drugs"@en, "Agents antiarythmiques"@fr, "Anti-Arrhythmic"@en, "Antiarythmisants"@fr, "Anti-Arrhythmia Agent"@en ;
  a skos:Concept, mesh:Descriptor ;
  dc:created "1975-07-25"^^xsd:date ;
  skos:hiddenLabel "Antifibrillatory Agents"@en, "Cardiac Depressant"@en, "Myocardial Depressants"@en, "Agents antifibrillants"@fr, "Antifibrillants"@fr, "Myocardial Depressant"@en, "Dépresseurs cardiaques"@fr, "Cardiac Depressants"@en, "Antifibrillatory Agent"@en, "Médicaments antifibrillants"@fr ;
  dc:modified "2020-05-27"^^xsd:date ;
  skos:inScheme jvr: ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D000889> ;
  skos:broader jvr:-P2SS2F17-G ;
  skos:definition "Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade."@en ;
  dc:established "1976-01-01"^^xsd:date .

jvr:-SZFZK4ZN-M mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-GSQSPFT0-D mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-LK745FB8-V
  skos:prefLabel "Coeur"@fr, "Heart"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:related jvr:-LS0SSBHQ-R .

jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-P2SS2F17-G
  skos:prefLabel "Cardiovascular Agents"@en, "Agents cardiovasculaires"@fr ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-LS0SSBHQ-R .

jvr:-P01MJBG5-L mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-M9FLW6ZC-B mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-MHWMGN6N-X mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .
jvr:-S3R185SD-K mesh:pharmacologicalAction jvr:-LS0SSBHQ-R .