@prefix jvr: <http://data.loterre.fr/ark:/67375/JVR> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix mesh: <http://id.nlm.nih.gov/mesh/vocab#> .
@prefix dc: <http://purl.org/dc/terms/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .

jvr:-H331X35G-9
  skos:prefLabel "(Pyridin-2-ylméthyl)sulfinyl-1H-benzimidazoles"@fr, "2-Pyridinylmethylsulfinylbenzimidazoles"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:narrower jvr:-L72LZP1Z-N .

jvr:-BT300B3G-Q
  skos:prefLabel "cerebrospinal fluid (Qualifier)"@en, "liquide cérébrospinal (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L6C0XPHT-4
  skos:prefLabel "métabolisme (Qualificatif)"@fr, "metabolism (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-XV06LPML-W
  skos:prefLabel "urine (Qualifier)"@en, "urine (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-Q3979798-W
  skos:prefLabel "analysis (Qualifier)"@en, "analyse (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-H7K65Q8S-Z
  skos:prefLabel "radiation effects (Qualifier)"@en, "effets des radiations (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-TJHVZCRZ-0
  skos:prefLabel "administration et posologie (Qualificatif)"@fr, "administration & dosage (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-G30ZJ446-J
  skos:prefLabel "toxicity (Qualifier)"@en, "toxicité (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NFTHND7Q-8
  skos:prefLabel "intoxication (Qualificatif)"@fr, "poisoning (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-FWD2BGQ0-9
  skos:prefLabel "usage thérapeutique (Qualificatif)"@fr, "therapeutic use (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-THHNVC7V-3
  skos:prefLabel "synthèse chimique (Qualificatif)"@fr, "chemical synthesis (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-R0ZCQ8X6-J
  skos:prefLabel "agonistes (Qualificatif)"@fr, "agonists (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-S0CS1X5R-5
  skos:prefLabel "immunology (Qualifier)"@en, "immunologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-M63HSDM7-1
  skos:prefLabel "antagonists & inhibitors (Qualifier)"@en, "antagonistes et inhibiteurs (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-HQRFT0C6-B
  skos:prefLabel "isolement et purification (Qualificatif)"@fr, "isolation & purification (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-NB0XHT3S-N
  skos:prefLabel "adverse effects (Qualifier)"@en, "effets indésirables (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-W6SQV79N-S
  skos:prefLabel "classification (Qualifier)"@en, "classification (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-CB30NGKB-3
  skos:prefLabel "economics (Qualifier)"@en, "économie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4R176S9-J
  skos:prefLabel "analogs & derivatives (Qualifier)"@en, "analogues et dérivés (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr: a skos:ConceptScheme .
jvr:-SBNWSM1T-R
  skos:prefLabel "history (Qualifier)"@en, "histoire (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-LD3NXJ47-1
  skos:prefLabel "Anti-Ulcer Agents"@en, "Antiulcéreux"@fr ;
  a mesh:Descriptor, skos:Concept .

jvr:-D0F21513-5
  skos:prefLabel "chemistry (Qualifier)"@en, "composition chimique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-R3QWLHRG-V
  skos:prefLabel "standards (Qualifier)"@en, "normes (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-NHL3D2X0-S
  skos:prefLabel "sang (Qualificatif)"@fr, "blood (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T9HQD7ST-J
  skos:prefLabel "ressources et distribution (Qualificatif)"@fr, "supply & distribution (Qualifier)"@en ;
  a mesh:Qualifier, skos:Concept .

jvr:-T6C9ZNTJ-G
  skos:prefLabel "Ésoméprazole"@fr, "Esomeprazole"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:broader jvr:-L72LZP1Z-N .

jvr:-NKM836P1-M
  skos:prefLabel "pharmacology (Qualifier)"@en, "pharmacologie (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-L72LZP1Z-N
  skos:hiddenLabel "Oméprazole de magnésium"@fr, "H 168-68"@en, "Prilosec"@en, "Oméprazole de sodium"@fr, "H168-68"@fr, "H-168-68"@fr, "Oméprazole magnésique"@fr, "Omeprazole Magnesium"@en, "H16868"@fr, "Oméprazole sodique"@fr, "Omeprazole Sodium"@en ;
  skos:inScheme jvr: ;
  mesh:allowableQualifier jvr:-THHNVC7V-3, jvr:-TJHVZCRZ-0, jvr:-L6C0XPHT-4, jvr:-NFTHND7Q-8, jvr:-NB0XHT3S-N, jvr:-W6SQV79N-S, jvr:-BT300B3G-Q, jvr:-G4R176S9-J, jvr:-R0ZCQ8X6-J, jvr:-WK5F724J-1, jvr:-SBNWSM1T-R, jvr:-XV06LPML-W, jvr:-D0F21513-5, jvr:-NHL3D2X0-S, jvr:-CB30NGKB-3, jvr:-R3QWLHRG-V, jvr:-NKM836P1-M, jvr:-T9HQD7ST-J, jvr:-H7K65Q8S-Z, jvr:-G30ZJ446-J, jvr:-Q3979798-W, jvr:-HQRFT0C6-B, jvr:-M63HSDM7-1, jvr:-FWD2BGQ0-9, jvr:-S0CS1X5R-5 ;
  skos:altLabel "1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-"@en, "1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-"@fr, "73590-58-6 (Omeprazole)"@en, "73590-58-6 (Omeprazole)"@fr, "KV03YZ6QLW"@fr, "KV03YZ6QLW"@en, "426QFE7XLK"@fr, "426QFE7XLK"@en, "KG60484QX9"@fr, "KG60484QX9"@en ;
  a mesh:Descriptor, skos:Concept ;
  skos:prefLabel "Oméprazole"@fr, "Omeprazole"@en ;
  mesh:pharmacologicalAction jvr:-LD3NXJ47-1, jvr:-G4JQ2Z44-D ;
  skos:definition "A 4-methoxy-3,5-dimethylpyridyl, 5-methoxybenzimidazole derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits an H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS."@en ;
  skos:narrower jvr:-T6C9ZNTJ-G ;
  dc:modified "2016-05-31"^^xsd:date ;
  dc:established "1987-01-01"^^xsd:date ;
  owl:sameAs <http://id.nlm.nih.gov/mesh/D009853> ;
  dc:created "1986-06-16"^^xsd:date ;
  skos:broader jvr:-H331X35G-9 .

jvr:-WK5F724J-1
  skos:prefLabel "pharmacokinetics (Qualifier)"@en, "pharmacocinétique (Qualificatif)"@fr ;
  a mesh:Qualifier, skos:Concept .

jvr:-G4JQ2Z44-D
  skos:prefLabel "Inhibiteurs de la pompe à protons"@fr, "Proton Pump Inhibitors"@en ;
  a mesh:Descriptor, skos:Concept .